Protein Alignment ninaB and rpe65a

DIOPT Version :9

• Sequence 1: NP_650307.2
• Gene: ninaB / 41678
• FlyBaseID: FBgn0002937
• Length: 620
• Species: Drosophila melanogaster
• Sequence 2: NP_957045.1
• Gene: rpe65a / 393724
• ZFINID: ZDB-GENE-040426-1717
• Length: 531
• Species: Danio rerio
• Alignment Length: 585
• Identity: 179/585 - (30%)
• Similarity: 288/585 - (49%)
• Gaps: 93/585 - (15%)

  Fly    52 EIVDPIEGHHSGHIPKWICGSLLRNGPGSWKVGDMTFGHLFDCSALLHRFAIRNGRVTYQNRFVD 116
            |:.:|:....:|.||.:|.|||||.|||.::.|...|.||||..||:|:|...||:|||..:||.
Zfish    21 ELNEPLPATVTGRIPSFIKGSLLRLGPGLFEAGAEPFYHLFDGQALMHKFDFSNGQVTYFRKFVK 85

  Fly   117 TETLRKNRSAQRIVVTEFGTAAVPDPCHSIFDRFAAIFRPDSGTDNSMISIYPFGDQYYTFTETP 181
            |:...:..:.:|:|:|||||.|.||||.:||.||.:.|:....|||.::::||.|:.:|..|||.
Zfish    86 TDAYVRAITEKRVVITEFGTCAYPDPCKNIFSRFFSYFKGVEVTDNCLVNVYPIGEDFYAVTETN 150

  Fly   182 FMHRINPCTLATEARICTTDFVGVVNHTSHPHVLPSGTVYNLGTTMTRSGP-AYTILSFPHGEQ- 244
            ::.::|..||.|..::...::|.:...|:|||:...|||||:|..|.:... ||.|:..|..::
Zfish   151 YITKVNVDTLETLKKVDMCNYVNINGVTAHPHIERDGTVYNIGNCMGKGASLAYNIVRIPPTQKD 215

  Fly   245 ---MFEDAHVVATLPCRWKLHPGYMHTFGLTDHYFVIVEQPLSVSLTEYIKA-QLGGQNLSACLK 305
               ..|.:.||...|...:..|.|:|:||:|::|||.||.|:.::|.:::.| .:.|.|...|.:
Zfish   216 KSDPIEKSKVVVQFPSAERFKPSYVHSFGMTENYFVFVETPVKINLLKFLSAWSIRGSNYMDCFE 280

  Fly   306 WFEDRPTLFHLIDRVSGKLVQ-TYESEAFFYLHIINCFERDGHVVVDICSYRNPEMI-NCMYLEA 368
            ..|::.|..|:..:..|:.:. .:.:.|....|.|||:|..|.:|.|:|:::..|.: |.::|
Zfish   281 SDEEKGTWIHIARKHPGEYIDYKFRTSAMGLFHHINCYEDSGFIVFDLCAWKGFEFVYNYLWL-- 343

  Fly   369 IANMQTNPNYATLFRGRPL-------RFVLPLGTIPPASIAKRGLVKSFSLAGLSAPQVSRTMKH 426
             ||::.  |:..:.|...:       |:|:||..
Zfish   344 -ANLRA--NWEEVKRNAMIAPQPEVRRYVIPLDP------------------------------- 374

  Fly   427 SVSQYADITYMPTNGKQATAGEESPKRDAKRGRYEEENLVNLVTMEGSQAEAFQGTNG-IQLRPE 490
                                             :.||...||:::..:.|.|....:| |.|.||
Zfish   375 ---------------------------------FREEQGKNLISLPYTTATATMRADGTIWLEPE 406

  Fly   491 MLCD---WGCETPRIYYERYMGKNYRYFYAISSDVDAVNPGTLIKVDVWNKSCLTWCEENVYPSE 552
            :|..   ...|.|:|.|....||||.|.|.:.  ::...|..:.|::|..|....|.|.:.||||
Zfish   407 VLFSGPRQAFEFPQINYRMVNGKNYTYAYGLG--LNHFVPDRICKLNVRTKETWVWQEPDSYPSE 469

  Fly   553 PIFVPSPDPKSEDDGVILASMVLGGLNDRYVGLIVLCAKTMTELGRCDFHTNGPVPKCLHGWFAP 617
            |:||.:||...||||:::..:|..|. .|....::|.||.::|:.|.:.....||  ..||.:.|
Zfish   470 PLFVQTPDGVDEDDGILMTIVVSPGA-QRPTYCLILNAKDLSEIARAEVEILTPV--TFHGMYKP 531

  Fly   618  617
            Zfish   532  531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ninaB	NP_650307.2	RPE65	52..617	CDD:281102	178/583 (31%)
rpe65a	NP_957045.1	RPE65	21..531	CDD:376981	178/583 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581443
Domainoid	1	1.000	353	1.000	Domainoid score	I958
eggNOG	1	0.900	-	-		E1_COG3670
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	357	1.000	Inparanoid score	I2188
OMA	1	1.010	-	-		QHG59724
OrthoDB	1	1.010	-	-		D342267at33208
OrthoFinder	1	1.000	-	-		FOG0000856
OrthoInspector	1	1.000	-	-		otm24986
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10543
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X319
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.870