DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment f-cup and PIRL6

DIOPT Version :9

Sequence 1:	NP_001262544.1	Gene:	f-cup / 41677	FlyBaseID:	FBgn0028487	Length:	802	Species:	Drosophila melanogaster
Sequence 2:	NP_179523.1	Gene:	PIRL6 / 816450	AraportID:	AT2G19330	Length:	380	Species:	Arabidopsis thaliana

Alignment Length:	454	Identity:	111/454 - (24%)
Similarity:	173/454 - (38%)	Gaps:	134/454 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 RSNPSTSRIPRSA-QSPRQASVVHSPRTNCAFRPIFHERSTHEDDQVLTQELWKLARKSGTLNLS 115
            |:|....|.|.|: .||...|...||::     |.|   :.:|::::            ..:|||
plant    24 RNNHQRKRSPLSSPSSPSSPSSPSSPKS-----PSF---NNNEEERL------------EVVNLS 68

  Fly   116 NKALARVPKRLYDINEADADSKAVNLEQLTIKEEDAWWNQVPLNNLDLSSNTLTHISPKI-ENLQ 179
            ..||..:|            :.::||.|:.              .||||:|.|..|...: ..|.
plant    69 GMALESLP------------NPSLNLAQIC--------------KLDLSNNHLQTIPESLTARLL 107

  Fly   180 SLTVLTLHDNALVELPPEIGKLEKLVRLNVSHNKLSQLPRAMYSLPELRHLNISYNEFVELNPDI 244
            :|..|.:|.|.:..||..||.|.||..||||.|.|...|:::.....|..||.::|:.:.
plant   108 NLIALDVHSNQIKALPNSIGCLSKLKTLNVSGNFLVSFPKSIQHCRSLEELNANFNKLIR----- 167

  Fly   245 SDLHMLEFLDGGHNNIQSLPGGIGF-LVRLTALLLPYNHIKELPPDLVNMRSLQKIDLMHNDLTS 308
                              ||..||| |..|..|.:..|.:..||..:.::.||:.:|...|.|..
plant   168 ------------------LPDSIGFELTNLRKLSINSNKLISLPISITHLTSLRVLDARLNCLMI 214

  Fly   309 LPEDMGLLRKLDCLYLQHNDILELPEFEGNEALNELHASNNFIKIIPKAMCSNLPHLKILDLRDN 373
            ||:|:                                              .||.:|:||::..|
plant   215 LPDDL----------------------------------------------ENLINLEILNVSQN 233

  Fly   374 --KITELPDELCLLRNLNRLDVSNNTISVLPVTLSSLAHLISLQVEGNPIKTIRRDILQCGTTRI 436
              .::.||..:.||.||..||||.|.|:|||.::..:..|..|.|||||:.:...::::.....:
plant   234 FQYLSALPSSIGLLMNLIELDVSYNKITVLPESIGCMRRLRKLSVEGNPLVSPPIEVMEQNLQVV 298

  Fly   437 LKTLHDRAVAKAKEEGGGVDDASTSAGISVTRL-RGGQMDDGDIPGNFPDSFHHQQQQNGFQCP 499
                  |.....|..||.....|........:| :.|..:.|....|       ::::.||..|
plant   299 ------REYLTQKMNGGSPRSPSKKKSWGFGKLVKYGTFNGGSRSWN-------REEREGFIMP 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
f-cup	NP_001262544.1	leucine-rich repeat	111..140	CDD:275380	6/28 (21%)
		LRR_RI	155..>377	CDD:238064	55/225 (24%)
		leucine-rich repeat	158..180	CDD:275380	8/22 (36%)
		LRR_8	180..235	CDD:290566	21/54 (39%)
		leucine-rich repeat	181..203	CDD:275380	9/21 (43%)
		leucine-rich repeat	204..226	CDD:275380	8/21 (38%)
		LRR_8	225..283	CDD:290566	13/58 (22%)
		leucine-rich repeat	227..249	CDD:275380	4/21 (19%)
		leucine-rich repeat	250..272	CDD:275380	6/22 (27%)
		LRR_8	272..329	CDD:290566	13/56 (23%)
		leucine-rich repeat	273..295	CDD:275380	5/21 (24%)
		leucine-rich repeat	296..318	CDD:275380	7/21 (33%)
		LRR_8	317..375	CDD:290566	6/59 (10%)
		leucine-rich repeat	319..340	CDD:275380	0/20 (0%)
		leucine-rich repeat	341..364	CDD:275380	2/22 (9%)
		leucine-rich repeat	389..410	CDD:275380	9/20 (45%)
		leucine-rich repeat	411..430	CDD:275380	7/18 (39%)
		leucine-rich repeat	627..650	CDD:275380
		leucine-rich repeat	651..669	CDD:275380
		leucine-rich repeat	697..719	CDD:275380
		LRR_8	719..777	CDD:290566
		leucine-rich repeat	720..743	CDD:275380
		leucine-rich repeat	744..766	CDD:275380
PIRL6	NP_179523.1	PRK15370	<55..>307	CDD:185268	89/364 (24%)
		leucine-rich repeat	62..84	CDD:275380	8/45 (18%)
		leucine-rich repeat	85..108	CDD:275380	8/36 (22%)
		leucine-rich repeat	109..131	CDD:275380	9/21 (43%)
		leucine-rich repeat	132..154	CDD:275380	8/21 (38%)
		leucine-rich repeat	155..178	CDD:275380	10/45 (22%)
		leucine-rich repeat	179..201	CDD:275380	5/21 (24%)
		leucine-rich repeat	202..224	CDD:275380	9/67 (13%)
		leucine-rich repeat	225..249	CDD:275380	8/23 (35%)
		leucine-rich repeat	250..272	CDD:275380	10/21 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45752
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010