DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment f-cup and CG3494

DIOPT Version :9

Sequence 1:	NP_001262544.1	Gene:	f-cup / 41677	FlyBaseID:	FBgn0028487	Length:	802	Species:	Drosophila melanogaster
Sequence 2:	NP_611915.1	Gene:	CG3494 / 37903	FlyBaseID:	FBgn0035008	Length:	240	Species:	Drosophila melanogaster

Alignment Length:	208	Identity:	104/208 - (50%)
Similarity:	145/208 - (69%)	Gaps:	2/208 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   596 YKLRHTRTLAVNLEELTSVPDQVFQIARDEGVHVVDFARNQLSTLPNGLQHMKDLVTELVLSNNV 660
            |.:|:||.|.|:..:::.||.:||:.|:.|.|::|....|:|..:|..|..:.:.:|:|||:.|.
  Fly    32 YHMRNTRILQVSKAQISEVPMEVFEAAQQELVNIVSLDGNRLLEMPKDLPLLSEHLTQLVLNKNQ 96

  Fly   661 IGYVPQFISQFTRISFLNLSNNLLNDLPTEFGVLNTLRELNIANNRFPCIPNCVYELQGLEILIA 725
            |.:||..|||:::::.|:||||||.|||.|.|.|..||.|:|::|||..:|.|:|||:.||.|.|
  Fly    97 ISFVPTNISQYSKLTNLSLSNNLLCDLPMELGGLRLLRNLDISHNRFRQLPRCIYELERLETLSA 161

  Fly   726 SENHIKMLNV--SGLQNMRRLSTLDLRNNDIETVPPILGNLTNITHLELVGNPFRQPRHQILMKG 788
            .:|.|:.::.  |||..||.|..|:|.||||:.||||||.:.|:..|||.||||||||||||..|
  Fly   162 HDNQIRAIDASESGLGGMRELKRLNLGNNDIQIVPPILGKMQNLVELELWGNPFRQPRHQILSMG 226

  Fly   789 TDAIMSYLRDRIP 801
            |.|::||||.|||
  Fly   227 TPALLSYLRTRIP 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
f-cup	NP_001262544.1	leucine-rich repeat	111..140	CDD:275380
		LRR_RI	155..>377	CDD:238064
		leucine-rich repeat	158..180	CDD:275380
		LRR_8	180..235	CDD:290566
		leucine-rich repeat	181..203	CDD:275380
		leucine-rich repeat	204..226	CDD:275380
		LRR_8	225..283	CDD:290566
		leucine-rich repeat	227..249	CDD:275380
		leucine-rich repeat	250..272	CDD:275380
		LRR_8	272..329	CDD:290566
		leucine-rich repeat	273..295	CDD:275380
		leucine-rich repeat	296..318	CDD:275380
		LRR_8	317..375	CDD:290566
		leucine-rich repeat	319..340	CDD:275380
		leucine-rich repeat	341..364	CDD:275380
		leucine-rich repeat	389..410	CDD:275380
		leucine-rich repeat	411..430	CDD:275380
		leucine-rich repeat	627..650	CDD:275380	6/22 (27%)
		leucine-rich repeat	651..669	CDD:275380	8/17 (47%)
		leucine-rich repeat	697..719	CDD:275380	12/21 (57%)
		LRR_8	719..777	CDD:290566	30/59 (51%)
		leucine-rich repeat	720..743	CDD:275380	10/24 (42%)
		leucine-rich repeat	744..766	CDD:275380	13/21 (62%)
CG3494	NP_611915.1	LRR	<34..>231	CDD:227223	96/196 (49%)
		leucine-rich repeat	38..62	CDD:275380	8/23 (35%)
		leucine-rich repeat	63..86	CDD:275380	6/22 (27%)
		LRR_4	85..124	CDD:289563	19/38 (50%)
		leucine-rich repeat	87..109	CDD:275380	11/21 (52%)
		leucine-rich repeat	110..133	CDD:275380	13/22 (59%)
		leucine-rich repeat	134..155	CDD:275380	11/20 (55%)
		leucine-rich repeat	156..181	CDD:275380	10/24 (42%)
		leucine-rich repeat	182..204	CDD:275380	13/21 (62%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459164
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0472
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D295141at33208
OrthoFinder	1	1.000	-	-		FOG0005608
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.750