DRSC/TRiP Functional Genomics Resources

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Protein Alignment f-cup and Lrch

DIOPT Version :9

Sequence 1:NP_001262544.1 Gene:f-cup / 41677 FlyBaseID:FBgn0028487 Length:802 Species:Drosophila melanogaster
Sequence 2:NP_609834.2 Gene:Lrch / 35041 FlyBaseID:FBgn0032633 Length:1135 Species:Drosophila melanogaster


Alignment Length:614 Identity:141/614 - (22%)
Similarity:220/614 - (35%) Gaps:179/614 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   201 LEKLV-------RLNVSHNKLSQLPR--AMYSLPELRHLNISYNEFVELNPDISDLHMLEFLDGG 256
            ||:::       .|.:::.||...||  ..|||.:....::|.|.|.||..:::....||.|...
  Fly    66 LERILEEAHFSGELILTNRKLKDFPRTGTKYSLTDTVIADLSRNRFAELPEEVTTFAFLETLLLY 130

  Fly   257 HNNIQSLPGGIGFLVRLTALLLPYNHIKELPPDLVNMRSLQKIDLMHNDLTSLPEDMGLLRKLDC 321
            ||.|:|:|..:..|..||.|.|..|.:..||.::..: .||.:.:.:|.|||||:::|.|     
  Fly   131 HNTIRSIPESVKQLSSLTYLDLRSNQLSSLPREICFL-PLQVLLVSNNRLTSLPDELGRL----- 189

  Fly   322 LYLQHNDILELPEFEGNEALNELHASNNFIKIIPKAMCSNLPHLKILDLRDNKITELPDEL-CLL 385
                            ::.|.:|.||.|.:..:| |....|..|:.|.||.|.:..||.|| || 
  Fly   190 ----------------DQTLTDLDASYNQLANLP-ARLGELRSLRSLSLRSNHLLYLPRELTCL- 236

  Fly   386 RNLNRLDVSNNTISVLPVTLSSLAHLISLQVEGNPIKTIRRDILQCGTTRILKTLHDRAV--AKA 448
             :|..||||||.|:.||:.:..::.|:.||:|.||:.:....:...|...:.|.|..:|.  .|.
  Fly   237 -SLISLDVSNNKIASLPLEIRHMSTLVELQLENNPLTSPPASLCMRGLVHVFKFLETQATKDEKG 300

  Fly   449 KEEGGGVD------------------DASTSAGISVTRLRGGQMDDG------------------ 477
            ...||..|                  :|||:.  |....|..|:|.|                  
  Fly   301 SRSGGNYDGYTTLRRAPRHNSSGNVLEASTTG--STNNQRRHQVDSGYNTSDGLDKRWSHDAPTK 363

  Fly   478 ----------------DIPGNFPDSFHHQQ---------------------QQNGFQCPCSY--- 502
                            .:|...|.:.|.|.                     ......|..||   
  Fly   364 SKTDSPLHCVSNSTAATLPRTLPSAVHSQADLMDASLTSSTSTIVDESLTLSPTASPCKLSYAHS 428

  Fly   503 --------PCQQQQM---QQQFCVY-------EPLRNCQEY----DRQTQGRIYEPENYQQQHQN 545
                    |.|...:   .|:..|:       :.|.|.|.|    :...|.|..|...|:|:|.|
  Fly   429 NSSSNGSSPDQDDDIMLDHQERTVHHANGRSGKGLGNIQTYKEYKEALKQQRNQEISVYKQKHPN 493

  Fly   546 GSLRSLFVQQQQQRMEYPYPGYFMYQQQQQQQFSYEQDPS----SRSAVHPRWVYKLRHTRTLAV 606
            .:                      :.....:..| ...||    |.|...|:.:.| :::..:..
  Fly   494 AN----------------------HSPNDDEDLS-PSPPSISNGSSSNTLPKSIMK-QNSNQIGH 534

  Fly   607 NLEELTSVPDQVFQIARDEGVHVVDFARNQL-STLPNGLQHMKDLVTELVLSNN---VIGYVPQF 667
            |.....|        |...||..|...:..: ..:|:.:..:|...|..:.|.|   .:|||...
  Fly   535 NGNGNGS--------ANGNGVDDVVIPKKPIQKVIPSRITEIKPASTSDIRSANSSDCLGYVKPQ 591

  Fly   668 ISQFTRISFLNLSNNLLNDLPTEFGVLNT 696
            .......|..|.||.  ..:.|..|::::
  Fly   592 SPMKNGTSKFNTSNG--GGVQTTVGIVSS 618

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
f-cupNP_001262544.1 leucine-rich repeat 111..140 CDD:275380
LRR_RI 155..>377 CDD:238064 54/184 (29%)
leucine-rich repeat 158..180 CDD:275380
LRR_8 180..235 CDD:290566 11/42 (26%)
leucine-rich repeat 181..203 CDD:275380 1/1 (100%)
leucine-rich repeat 204..226 CDD:275380 8/30 (27%)
LRR_8 225..283 CDD:290566 19/57 (33%)
leucine-rich repeat 227..249 CDD:275380 5/21 (24%)
leucine-rich repeat 250..272 CDD:275380 9/21 (43%)
LRR_8 272..329 CDD:290566 17/56 (30%)
leucine-rich repeat 273..295 CDD:275380 7/21 (33%)
leucine-rich repeat 296..318 CDD:275380 10/21 (48%)
LRR_8 317..375 CDD:290566 13/57 (23%)
leucine-rich repeat 319..340 CDD:275380 0/20 (0%)
leucine-rich repeat 341..364 CDD:275380 8/22 (36%)
leucine-rich repeat 389..410 CDD:275380 9/20 (45%)
leucine-rich repeat 411..430 CDD:275380 6/18 (33%)
leucine-rich repeat 627..650 CDD:275380 4/23 (17%)
leucine-rich repeat 651..669 CDD:275380 6/20 (30%)
leucine-rich repeat 697..719 CDD:275380 141/614 (23%)
LRR_8 719..777 CDD:290566
leucine-rich repeat 720..743 CDD:275380
leucine-rich repeat 744..766 CDD:275380
LrchNP_609834.2 LRR_8 124..179 CDD:290566 19/55 (35%)
LRR_4 124..161 CDD:289563 14/36 (39%)
leucine-rich repeat 124..146 CDD:275380 9/21 (43%)
leucine-rich repeat 147..167 CDD:275380 7/19 (37%)
leucine-rich repeat 169..192 CDD:275380 10/43 (23%)
leucine-rich repeat 193..215 CDD:275380 8/22 (36%)
leucine-rich repeat 216..237 CDD:275380 11/22 (50%)
leucine-rich repeat 238..260 CDD:275380 10/21 (48%)
leucine-rich repeat 261..279 CDD:275380 6/17 (35%)
CH 676..756 CDD:214479
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45467268
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.840

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