Protein Alignment f-cup and Lrch

DIOPT Version :10

• Sequence 1: NP_001262544.1
• Gene: f-cup / 41677
• FlyBaseID: FBgn0028487
• Length: 802
• Species: Drosophila melanogaster
• Sequence 2: NP_609834.2
• Gene: Lrch / 35041
• FlyBaseID: FBgn0032633
• Length: 1135
• Species: Drosophila melanogaster
• Alignment Length: 614
• Identity: 141/614 - (22%)
• Similarity: 220/614 - (35%)
• Gaps: 179/614 - (29%)

  Fly   201 LEKLV-------RLNVSHNKLSQLPR--AMYSLPELRHLNISYNEFVELNPDISDLHMLEFLDGG 256
            ||:::       .|.:::.||...||  ..|||.:....::|.|.|.||..:::....||.|...
  Fly    66 LERILEEAHFSGELILTNRKLKDFPRTGTKYSLTDTVIADLSRNRFAELPEEVTTFAFLETLLLY 130

  Fly   257 HNNIQSLPGGIGFLVRLTALLLPYNHIKELPPDLVNMRSLQKIDLMHNDLTSLPEDMGLLRKLDC 321
            ||.|:|:|..:..|..||.|.|..|.:..||.::..: .||.:.:.:|.|||||:::|.|
  Fly   131 HNTIRSIPESVKQLSSLTYLDLRSNQLSSLPREICFL-PLQVLLVSNNRLTSLPDELGRL----- 189

  Fly   322 LYLQHNDILELPEFEGNEALNELHASNNFIKIIPKAMCSNLPHLKILDLRDNKITELPDEL-CLL 385
                            ::.|.:|.||.|.:..:| |....|..|:.|.||.|.:..||.|| ||
  Fly   190 ----------------DQTLTDLDASYNQLANLP-ARLGELRSLRSLSLRSNHLLYLPRELTCL- 236

  Fly   386 RNLNRLDVSNNTISVLPVTLSSLAHLISLQVEGNPIKTIRRDILQCGTTRILKTLHDRAV--AKA 448
             :|..||||||.|:.||:.:..::.|:.||:|.||:.:....:...|...:.|.|..:|.  .|.
  Fly   237 -SLISLDVSNNKIASLPLEIRHMSTLVELQLENNPLTSPPASLCMRGLVHVFKFLETQATKDEKG 300

  Fly   449 KEEGGGVD------------------DASTSAGISVTRLRGGQMDDG------------------ 477
            ...||..|                  :|||:.  |....|..|:|.|
  Fly   301 SRSGGNYDGYTTLRRAPRHNSSGNVLEASTTG--STNNQRRHQVDSGYNTSDGLDKRWSHDAPTK 363

  Fly   478 ----------------DIPGNFPDSFHHQQ---------------------QQNGFQCPCSY--- 502
                            .:|...|.:.|.|.                     ......|..||
  Fly   364 SKTDSPLHCVSNSTAATLPRTLPSAVHSQADLMDASLTSSTSTIVDESLTLSPTASPCKLSYAHS 428

  Fly   503 --------PCQQQQM---QQQFCVY-------EPLRNCQEY----DRQTQGRIYEPENYQQQHQN 545
                    |.|...:   .|:..|:       :.|.|.|.|    :...|.|..|...|:|:|.|
  Fly   429 NSSSNGSSPDQDDDIMLDHQERTVHHANGRSGKGLGNIQTYKEYKEALKQQRNQEISVYKQKHPN 493

  Fly   546 GSLRSLFVQQQQQRMEYPYPGYFMYQQQQQQQFSYEQDPS----SRSAVHPRWVYKLRHTRTLAV 606
            .:                      :.....:..| ...||    |.|...|:.:.| :::..:..
  Fly   494 AN----------------------HSPNDDEDLS-PSPPSISNGSSSNTLPKSIMK-QNSNQIGH 534

  Fly   607 NLEELTSVPDQVFQIARDEGVHVVDFARNQL-STLPNGLQHMKDLVTELVLSNN---VIGYVPQF 667
            |.....|        |...||..|...:..: ..:|:.:..:|...|..:.|.|   .:|||...
  Fly   535 NGNGNGS--------ANGNGVDDVVIPKKPIQKVIPSRITEIKPASTSDIRSANSSDCLGYVKPQ 591

  Fly   668 ISQFTRISFLNLSNNLLNDLPTEFGVLNT 696
            .......|..|.||.  ..:.|..|::::
  Fly   592 SPMKNGTSKFNTSNG--GGVQTTVGIVSS 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
f-cup	NP_001262544.1	LRR	98..428	CDD:443914	76/236 (32%)
		leucine-rich repeat	111..140	CDD:275380
		leucine-rich repeat	158..180	CDD:275380
		leucine-rich repeat	181..203	CDD:275380	1/1 (100%)
		leucine-rich repeat	204..226	CDD:275380	8/30 (27%)
		leucine-rich repeat	227..249	CDD:275380	5/21 (24%)
		leucine-rich repeat	250..272	CDD:275380	9/21 (43%)
		leucine-rich repeat	273..295	CDD:275380	7/21 (33%)
		leucine-rich repeat	296..318	CDD:275380	10/21 (48%)
		leucine-rich repeat	319..340	CDD:275380	0/20 (0%)
		leucine-rich repeat	341..364	CDD:275380	8/22 (36%)
		leucine-rich repeat	389..410	CDD:275380	9/20 (45%)
		leucine-rich repeat	411..430	CDD:275380	6/18 (33%)
		leucine-rich repeat	627..650	CDD:275380	4/23 (17%)
		LRR	<629..>778	CDD:443914	15/72 (21%)
		leucine-rich repeat	651..669	CDD:275380	6/20 (30%)
		leucine-rich repeat	697..719	CDD:275380	141/614 (23%)
		leucine-rich repeat	720..743	CDD:275380
		leucine-rich repeat	744..766	CDD:275380
Lrch	NP_609834.2	LRR	<81..>286	CDD:443914	74/229 (32%)
		leucine-rich repeat	124..146	CDD:275380	9/21 (43%)
		leucine-rich repeat	147..167	CDD:275380	7/19 (37%)
		leucine-rich repeat	169..192	CDD:275380	10/43 (23%)
		leucine-rich repeat	193..215	CDD:275380	8/22 (36%)
		leucine-rich repeat	216..237	CDD:275380	11/22 (50%)
		leucine-rich repeat	238..260	CDD:275380	10/21 (48%)
		leucine-rich repeat	261..279	CDD:275380	6/17 (35%)
		CH_LRCH	667..755	CDD:409054
		CH_SF	<1075..1099	CDD:469584