Protein Alignment f-cup and fliI

DIOPT Version :10

• Sequence 1: NP_001262544.1
• Gene: f-cup / 41677
• FlyBaseID: FBgn0028487
• Length: 802
• Species: Drosophila melanogaster
• Sequence 2: NP_525097.1
• Gene: fliI / 33110
• FlyBaseID: FBgn0000709
• Length: 1256
• Species: Drosophila melanogaster
• Alignment Length: 482
• Identity: 125/482 - (25%)
• Similarity: 203/482 - (42%)
• Gaps: 129/482 - (26%)

  Fly   112 LNLSNKALARVPKRLYDINEADADSKAVNLEQLTIKEEDAWWNQVP-----------LNNLDLSS 165
            |.|....||.:|:.|..:.:         ||.|::..     |::.           |.:|||..
  Fly    34 LTLDRTQLAEIPEELGHLQK---------LEHLSLNH-----NRLEKIFGELTELSCLRSLDLRH 84

  Fly   166 NTLTH--ISPKIENLQSLTVLTLHDNALVELPPEIGKLEKLVRLNVSHNKLSQLPRAMY-SLPEL 227
            |.|.:  |.|::.:|:.||.|.|..|.|.|:|..:.:.:.|:.||:|:|::..:|..:: .|.:|
  Fly    85 NQLKNSGIPPELFHLEELTTLDLSHNKLKEVPEGLERAKNLIVLNLSNNQIESIPTPLFIHLTDL 149

  Fly   228 RHLNISYNEFVELNPDISDLHMLEFLDGGHN-----------NIQSL---------------PGG 266
            ..|::|:|....|.|....|..|:.||..||           ::|||               |..
  Fly   150 LFLDLSHNRLETLPPQTRRLINLKTLDLSHNPLELFQLRQLPSLQSLEVLKMSGTQRTLLNFPTS 214

  Fly   267 IGFLVRLTALLLPYNHIKELPPDLVNMRSLQKIDLMHNDLTSLPEDMGLLRKLDCLYLQHNDILE 331
            |..|..|..|.|.:|.:.:||..:.|:.:|.:::|..|:||.|...:.|.::|:.|.|..|.::.
  Fly   215 IDSLANLCELDLSHNSLPKLPDCVYNVVTLVRLNLSDNELTELTAGVELWQRLESLNLSRNQLVA 279

  Fly   332 LP-------------------EFEGNE-------ALNELHASNNFIKIIPKAMCSNLPHLKILDL 370
            ||                   .|||..       ||....|:||.::::|:.:| ....||.|:|
  Fly   280 LPAALCKLPKLRRLLVNDNKLNFEGIPSGIGKLGALEVFSAANNLLEMVPEGLC-RCGALKQLNL 343

  Fly   371 RDNKITELPDELCLLRNLNRLDVSNNTISVLPVTLSSLAHLISLQ-------------VEGNPI- 421
            ..|::..|||.:.||..|::||:.||...|:|...|..:...||:             :.|..:
  Fly   344 SCNRLITLPDAIHLLEGLDQLDLRNNPELVMPPKPSEASKATSLEFYNIDFSLQTQLRLAGAAVP 408

  Fly   422 -----------KTIRRDILQCG--------TTRILKTLHDRAVAKAKE-EGGGVDDASTSAGISV 466
                       .|.|:..|:.|        ..::||.:.|  |||.|: |.|.|.:......:..
  Fly   409 PSMPSSATPKDSTARKIRLRRGPRSEGDQDAAKVLKGMKD--VAKDKDNEAGAVPEDGKPESLKP 471

  Fly   467 TR----LRGGQM--------DDGDIPG 481
            .|    |...|:        |||.:||
  Fly   472 KRWDESLEKPQLDYSKFFEKDDGQLPG 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
f-cup	NP_001262544.1	LRR	98..428	CDD:443914	105/406 (26%)
		leucine-rich repeat	111..140	CDD:275380	6/27 (22%)
		leucine-rich repeat	158..180	CDD:275380	9/23 (39%)
		leucine-rich repeat	181..203	CDD:275380	8/21 (38%)
		leucine-rich repeat	204..226	CDD:275380	7/22 (32%)
		leucine-rich repeat	227..249	CDD:275380	7/21 (33%)
		leucine-rich repeat	250..272	CDD:275380	11/47 (23%)
		leucine-rich repeat	273..295	CDD:275380	7/21 (33%)
		leucine-rich repeat	296..318	CDD:275380	7/21 (33%)
		leucine-rich repeat	319..340	CDD:275380	9/46 (20%)
		leucine-rich repeat	341..364	CDD:275380	6/22 (27%)
		leucine-rich repeat	389..410	CDD:275380	7/20 (35%)
		leucine-rich repeat	411..430	CDD:275380	5/43 (12%)
		leucine-rich repeat	627..650	CDD:275380
		LRR	<629..>778	CDD:443914
		leucine-rich repeat	651..669	CDD:275380
		leucine-rich repeat	697..719	CDD:275380
		leucine-rich repeat	720..743	CDD:275380
		leucine-rich repeat	744..766	CDD:275380
fliI	NP_525097.1	leucine-rich repeat	7..30	CDD:275380
		leucine-rich repeat	31..53	CDD:275380	6/18 (33%)
		LRR	33..405	CDD:443914	102/385 (26%)
		leucine-rich repeat	54..76	CDD:275380	4/26 (15%)
		leucine-rich repeat	77..101	CDD:275380	9/23 (39%)
		leucine-rich repeat	102..124	CDD:275380	8/21 (38%)
		leucine-rich repeat	125..148	CDD:275380	7/22 (32%)
		leucine-rich repeat	149..171	CDD:275380	7/21 (33%)
		leucine-rich repeat	172..195	CDD:275380	5/22 (23%)
		leucine-rich repeat	196..220	CDD:275380	4/23 (17%)
		leucine-rich repeat	221..243	CDD:275380	7/21 (33%)
		leucine-rich repeat	244..266	CDD:275380	7/21 (33%)
		leucine-rich repeat	267..289	CDD:275380	6/21 (29%)
		leucine-rich repeat	290..314	CDD:275380	3/23 (13%)
		leucine-rich repeat	315..335	CDD:275380	6/20 (30%)
		leucine-rich repeat	338..360	CDD:275378	10/21 (48%)
		gelsolin_S1_like	491..602	CDD:200446	5/8 (63%)
		gelsolin_like	618..706	CDD:200436
		gelsolin_S3_like	729..828	CDD:200448
		gelsolin_like	920..1015	CDD:200436
		gelsolin_S5_like	1037..1141	CDD:200444
		gelsolin_S6_like	1151..1250	CDD:200447