DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14367 and cfap36

DIOPT Version :9

Sequence 1:	NP_650305.1	Gene:	CG14367 / 41676	FlyBaseID:	FBgn0038170	Length:	310	Species:	Drosophila melanogaster
Sequence 2:	NP_001035412.1	Gene:	cfap36 / 678564	ZFINID:	ZDB-GENE-060421-8162	Length:	349	Species:	Danio rerio

Alignment Length:	393	Identity:	103/393 - (26%)
Similarity:	159/393 - (40%)	Gaps:	128/393 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSVEDSWVFDSLVCFLHGPIWNAPLQTFIEQKSLVFDPNQQLDENNPDILQIHEEYKNLVDYMLG 65
            |:.:..||.:|:..||..|.|..||..|:|.:..|||..   |||.....:||::||.||:.:|.
Zfish     1 MAEDSEWVPESIAGFLGSPDWLIPLAEFMESRCSVFDDE---DENKLTYTEIHQQYKQLVERLLE 62

  Fly    66 SFMEEMQISPEQFEMACLEGRQQGQGENPFHFHQVLFQQIWAANDLKIFIRMMTQRNVELQLQAL 130
            ::|:::.||.:||..||........       .|.:||.:.|.:|.::|..:|.|:|:|||||||
Zfish    63 NYMQDVGISEQQFLEACSSFSSSAS-------LQTVFQPVLATDDFQMFRSLMVQKNMELQLQAL 120

  Fly   131 DLIEKNQLAPGGVEE----------------------------------------GDDRSADASS 155
            .:|::..   ||:.|                                        |.:..|..||
Zfish   121 HVIKQRN---GGLPECLTDGVDVMSELEQQEMKILQEVLRRSKEEYDLQMGQCGLGSEDLASTSS 182

  Fly   156 DPGDTASEVEQMIAKTVSD--------------------ELESPEAALT---------------- 184
            ...:|....||.::..|||                    ::||...|.|
Zfish   183 SVSETPQNPEQRLSNGVSDPLTLTQPDSEMEESSTATQRKMESEPTATTACKSKALPAVRAPLRG 247

  Fly   185 --------PEQEPNLELVNDKFQRLNLFFEQEDRVDPSDVVSRQEYLRQQRDKIVEIKKQTRAKQ 241
                    .|:|..||...|...      :.....|...:..|.|||:|||||:..:|:|| .|.
Zfish   248 SVCAKQSSAERERELERARDTHT------DCRTLTDEVALQQRSEYLKQQRDKLQALKRQT-GKG 305

  Fly   242 LQETMSRGTPHAPEGARPSSALVAQQLLENGGQTKELSMPAPLEAEENAALQLRRNLAKRLRSEV 306
            |.:|.:..||      .|..|            |:|:|:      ||...||.|:::|::|:.||
Zfish   306 LTDTAAAATP------EPKPA------------TQEISV------EEKKKLQKRKHVAEKLKEEV 346

  Fly   307 VEQ 309
            :::
Zfish   347 IKK 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14367	NP_650305.1	ARL2_Bind_BART	9..125	CDD:288392	38/115 (33%)
cfap36	NP_001035412.1	ARL2_Bind_BART	10..115	CDD:288392	38/114 (33%)
cfap36	NP_001035412.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	300..336		16/60 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587255
Domainoid	1	1.000	77	1.000	Domainoid score	I8819
eggNOG	1	0.900	-	-		E1_KOG4511
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	104	1.000	Inparanoid score	I4940
OMA	1	1.010	-	-		QHG48653
OrthoDB	1	1.010	-	-		D1373952at2759
OrthoFinder	1	1.000	-	-		FOG0006980
OrthoInspector	1	1.000	-	-		oto39705
orthoMCL	1	0.900	-	-		OOG6_105908
Panther	1	1.100	-	-	LDO	PTHR21532
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4195
SonicParanoid	1	1.000	-	-		X5871
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800