DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14367 and cfap-36

DIOPT Version :9

Sequence 1:	NP_650305.1	Gene:	CG14367 / 41676	FlyBaseID:	FBgn0038170	Length:	310	Species:	Drosophila melanogaster
Sequence 2:	NP_503147.1	Gene:	cfap-36 / 190931	WormBaseID:	WBGene00022435	Length:	685	Species:	Caenorhabditis elegans

Alignment Length:	256	Identity:	72/256 - (28%)
Similarity:	126/256 - (49%)	Gaps:	29/256 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 FLHGPIWNAPLQTFIEQKSLVFDPNQQLDENNPDI-LQIHEEYKNLVDYMLGSFMEEMQISPEQF 78
            |:...||:.|:.:|||.:|:||| .||::   .|: :.||:||..|:|.::..|.|::..:|.:.
Worm    33 FITSSIWSIPIASFIESQSVVFD-RQQME---TDVYIMIHKEYSQLIDTLIECFCEDVGTTPTEL 93

  Fly    79 EMACLEGRQQGQGENPFHFHQVLFQQIWAANDLKIFIRMMTQRNVELQLQALDLIE-KNQLAPG- 141
            ..|.....|:...:.    ::|..:.:.||.:..:|:.||.::|:|||||||.:|| ...|.|.
Worm    94 VAAIQLFNQKDVSQQ----YKVALEPLLAAQNFNVFVPMMMRKNIELQLQALQMIEFMCGLIPSV 154

  Fly   142 -GVEEGDDRSADASSDPGDTASEVEQMIAKTVSDELESPEAALTPEQEPNLELVNDKFQRLNLFF 205
             .:|:|:.........|.:|...|...:.:...||.:|.:..   .:|..:...|.:.||..|
Worm   155 LQLEDGETLRNMKKLSPEETERYVLISVLRHSKDEYDSMQKG---SEELEMMAQNSRIQREAL-- 214

  Fly   206 EQEDRVDPSDVVSRQEYLRQQR-DKIVEIKKQTRAKQLQETMSRGTPHAPEGARPSSALVA 265
            |||        :.::|.|.||. |:....:.|.:.:....|.:.|. :||  .|..:|::|
Worm   215 EQE--------IRKEEILLQQALDEGARAQNQNQNQGTSSTQTDGV-NAP--LRSVAAMMA 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14367	NP_650305.1	ARL2_Bind_BART	9..125	CDD:288392	32/110 (29%)
cfap-36	NP_503147.1	ARL2_Bind_BART	31..136	CDD:314433	32/110 (29%)
cfap-36	NP_503147.1	Herpes_ICP4_C	289..>546	CDD:332854
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162615
Domainoid	1	1.000	63	1.000	Domainoid score	I6813
eggNOG	1	0.900	-	-		E1_KOG4511
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006980
OrthoInspector	1	1.000	-	-		oto19258
orthoMCL	1	0.900	-	-		OOG6_105908
Panther	1	1.100	-	-	LDO	PTHR21532
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4195
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.730