DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment flfl and AT5G49390

DIOPT Version :9

Sequence 1:	NP_731849.2	Gene:	flfl / 41675	FlyBaseID:	FBgn0024555	Length:	980	Species:	Drosophila melanogaster
Sequence 2:	NP_001318767.1	Gene:	AT5G49390 / 834999	AraportID:	AT5G49390	Length:	826	Species:	Arabidopsis thaliana

Alignment Length:	1027	Identity:	247/1027 - (24%)
Similarity:	431/1027 - (41%)	Gaps:	261/1027 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 TDTRRRVKLYALNAERQWDDRGTGHVSSTYVERLKGISLLVRAESDGSLLLESKIQPDTAYQKQQ 67
            |::.:|||:|.||.:.||||:||||::..|:||.:..:|.|..|.|.:.||..:|..|..|::|.
plant     7 TNSMQRVKVYRLNEDGQWDDKGTGHITMDYMERSEVFNLYVIDEDDNATLLAHRISIDNIYKQQD 71

  Fly    68 DTLIVWSEGD-NFDLALSFQEKAGCDEIWEKICQVQG----KDPSVEITQDIVEESEDERFEDMS 127
            |::|.|.:.. :..|||||||.|||..:|.:|..:|.    ...:.|...:::.|.:
plant    72 DSIISWIDPQHSAQLALSFQETAGCTIVWNQISSMQRILHFDSLNSEAFHNVISELK-------- 128

  Fly   128 DTAPPIELPPCELSRLEDISETIQSCLSTPLRKEKLSMALESESYIKKLLNLFHVCEDLDNTEGL 192
                  |||...:|.|..|.:.:....:|...:....|.....::.:||:::|..||:..:.:||
plant   129 ------ELPDVNISNLPLILKVVADYGNTDQMRLTELMLKNQGAFFQKLIDVFDDCENRKDIDGL 187

  Fly   193 HHLFEIFKNIFLLNKNALFEIMFADDTIFDVVGCLEYDPSVSQPKKHRQYLKQLAKFREAVPIKN 257
            |.:|.|.|.|..:|...:.||:..|.....:.|||||||.|.|.|.||..|::...|.|.:||||
plant   188 HMMFNIVKEIISVNNYQILEIILGDQLFMKIFGCLEYDPDVPQSKDHRTSLRKNVVFVEDIPIKN 252

  Fly   258 LDLLAKIHQTFRVQYIQDIILP-----TPSVFVEDNMLNTLSSFIFFNKVEIVTMIQDDERYLLD 317
            ..:|:|||||:|:.:::|::|.     ..|.|: |:::|.       ||..::|:::||   :.:
plant   253 PLVLSKIHQTYRIDFLKDVVLTDVLDVATSAFL-DSVINA-------NKATVLTLLKDD---IQE 306

  Fly   318 VFAVLTDPTTGDAKRRDTVLFLKEFCNYAQNLQPQGKDSFYKTLTCLGILQALELTLVMNDKKTK 382
            .||.|..|:|.|..|.:.|.||.|||:....   :...|..:.|..:|:...:...|:.:|||..
plant   307 SFARLRSPSTSDESRNNLVYFLLEFCSLCTK---EKNVSVLRELIRVGLFDIIAEVLMSSDKKLV 368

  Fly   383 SASIDILTAIVEFSPLVVRNYTLNQANRPEVERMLLNIAIEQMLNDSEPEL-GIAVQLM------ 440
            .....||:.::....:.:.:|.:    |||.  .||.:.::.|:.|...|: .:.|.::
plant   369 LMGAKILSVLLAQDSIRLCSYVV----RPET--YLLGLLVKGMMEDFGDEMESLFVDIIQNVLGC 427

  Fly   441 GIVKILLEPENM------------LTEKGDFLNFFYKYSVQTLVAPVILNTIGDRPQNEDYQTAQ 493
            |..::..:..||            |.|..||                |:.:..:||.:.......
plant   428 GGAQVSDKKTNMQRIIWDIFCEKHLPELVDF----------------IMASCPERPGDTSEGAFV 476

  Fly   494 LLGI-----------VLDILSFCVEHHSYHIKNFLLQKDLLKRILVLMKSTHTFLVLGALRLLRK 547
            .:|.           :.::|..||:..... .|| |...:::::|:|.:.....||..|:|.:|.
plant   477 RVGSHRGTKPGILLRICELLCSCVQLDPSR-TNF-LHNSVIEKVLLLTRRKEKTLVAAAVRFVRT 539

  Fly   548 IIALKDEFYNRHIVKCNLFAPVVDAFIRNNGRYNLLESAILELFEFIKLEDIRTLCVYFVENFSK 612
            ::::.::....:||:.|...|:::.|:.|..|.||:.:|:|||.|.|: ::...|..|..:.|..
plant   540 LLSVHNDNVQSYIVENNTLKPIIEVFVANRHRDNLMTAAVLELLEHIR-KEYAVLVKYVGDTFWD 603

  Fly   613 IFDEIEYVQTFKYLKNRYDQYQDRLKDRDKMENRTDGGLPIIRSGGRFRRDQRQMEEEEEMWFNE 677
            .....|.:::.|.||.:|::......| |:.:.|.||               |.::|
plant   604 QLAPFENLRSIKDLKTKYEKGPKSTTD-DESDMRQDG---------------RALDE-------- 644

  Fly   678 EDDFTEEIDTYNNVMKSVSEKNGPQTQNQQKSSPPHSTSPHSGLLGSLSTTASSTATSATSGAPV 742
                               :|....:..|.:.:.||::          :.||:|:|:|.
plant   645 -------------------KKPASASSTQMEEADPHNS----------NATAASSASST------ 674

  Fly   743 ASGSSSPEAISADEQTQAAVHLAAAALQHHQQQQQQQQQNPFQQQTQPEIAELQQQLSSVEAPQS 807
                                              |.:...|:    .|::.    ..||..:.|.
plant   675 ----------------------------------QMEDAEPY----NPDVT----AASSTCSTQM 697

  Fly   808 QELELSQSAAASASPTSSSSSLEASTSSSSASSSSSSSSSSSPPGSSAAASLCDSATVAAVAASQ 872
            :..|.......:||.|||:...||...:...:::||:|.:.
plant   698 EVAEPYNPGVTAASSTSSTQMEEADPYNPDVTAASSTSITP------------------------ 738

  Fly   873 FLSTIATAMAASVTAAAATNSSPSISPAPAVSSPDIENADAQLPPSDDASSPASGEQDANSTEGT 937
              ..:|......||||::|:.:|            :|.|:...|....|||.:..::..
plant   739 --MEVAEPYNPDVTAASSTSITP------------MEVAEPYNPGVTAASSVSPSKRSG------ 783

  Fly   938 SSEADKTTAKKGLVDYESDSGEDDYEEDE------YSEG----PQAQKRARQ 979
                       ||||||.|  ||:.|:.:      .|||    |:....|::
plant   784 -----------GLVDYEDD--EDELEKSKRQKLSSTSEGNKNTPEQGGEAKE 822

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
flfl	NP_731849.2	PH-like	8..>66	CDD:302622	26/57 (46%)
flfl	NP_731849.2	SMK-1	169..361	CDD:282636	67/196 (34%)
AT5G49390	NP_001318767.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	141	1.000	Domainoid score	I1520
eggNOG	1	0.900	-	-		E1_KOG2175
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	374	1.000	Inparanoid score	I553
OMA	1	1.010	-	-		QHG54949
OrthoDB	1	1.010	-	-		D388216at2759
OrthoFinder	1	1.000	-	-		FOG0001376
OrthoInspector	1	1.000	-	-		otm2943
orthoMCL	1	0.900	-	-		OOG6_101106
Panther	1	1.100	-	-	O	PTHR23318
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X869
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.880