DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment flfl and AT3G06670

DIOPT Version :9

Sequence 1:	NP_731849.2	Gene:	flfl / 41675	FlyBaseID:	FBgn0024555	Length:	980	Species:	Drosophila melanogaster
Sequence 2:	NP_001189831.1	Gene:	AT3G06670 / 819852	AraportID:	AT3G06670	Length:	886	Species:	Arabidopsis thaliana

Alignment Length:	905	Identity:	263/905 - (29%)
Similarity:	458/905 - (50%)	Gaps:	111/905 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 TDTRRRVKLYALNAERQWDDRGTGHVSSTYVERLKGISLLVRAESDGSLLLESKIQPDTAYQKQQ 67
            |::.:|||:|.||.:.:||||||||||..:|||.:.:||.|..|.|...||...|.|:..|:||:
plant    11 TNSMQRVKVYHLNEDGKWDDRGTGHVSIDFVERSEELSLCVIDEEDNETLLVHPINPEDIYRKQE 75

  Fly    68 DTLIVWSEGD-NFDLALSFQEKAGCDEIWEKICQVQGKDPSVEITQDIVEES-EDERFEDMSDTA 130
            ||:|.|.:.: :.:|||||||.|||..:|::||.:|         :::...| ..|.|..::...
plant    76 DTIISWRDPERSTELALSFQETAGCSYVWDQICTMQ---------RNLHFSSLNSETFHSLNSEL 131

  Fly   131 PPIELPPCELSRLEDISETI-QSCLSTPLRKEKLSMALESESYIKKLLNLFHVCEDLDNTEGLHH 194
            .  |||..||:.|..|.:.: :|.::..:|..:|  .|:...:.:.|:.:|.:||||:|.:|||.
plant   132 R--ELPAVELTTLPLILKIVTESGITDQMRLTEL--ILKDHDFFRNLMGVFKICEDLENVDGLHM 192

  Fly   195 LFEIFKNIFLLNKNALFEIMFADDTIFDVVGCLEYDPSVSQPKKHRQYLKQLAKFRE-------- 251
            :|.|.|.|.|||.:.:.|.:|.|:.|.:::|||||||.|...:.||.:||:...|:|
plant   193 IFNIVKGIILLNSSQILEKIFGDELIMEIIGCLEYDPGVPHSQHHRNFLKEHVVFKERQSHVFFV 257

  Fly   252 -------------AVPIKNLDLLAKIHQTFRVQYIQDIILPTPSVFVEDNMLNTLSSFIFFNKVE 303
                         |:|||:..:|:|||||:|:.|::|::|   :..::|.::..|:|.|..|...
plant   258 RKEHAHYGCFGISAIPIKDPLVLSKIHQTYRIGYLKDVVL---ARVLDDAIVANLNSVIHANNAI 319

  Fly   304 IVTMIQDDERYLLDVFAVLTDPTTGDAKRRDTVLFLKEFCNYAQNLQPQGKDSFYKTLTCLGILQ 368
            :|::::||..::.::||.|..|:|....:::.|.||.|||:.:::||...:...::.|...||..
plant   320 VVSLLKDDSTFIQELFARLRSPSTSMESKKNLVYFLHEFCSLSKSLQVVQQLRLFRDLINEGIFH 384

  Fly   369 ALELTLVMNDKKTKSASIDILTAIVEFSPLVVRNYTLNQANRPEVERMLLNIAIEQMLNDSEPEL 433
            .:|..|.:.|||......|||...:...|.::|:|.:.....|     ||.:.::.|:.|...::
plant   385 VIEEVLQIPDKKLVLTGTDILILFLTQDPNLLRSYVVRTEGNP-----LLGLLVKGMMEDFGDKM 444

  Fly   434 GIAVQLMGIVKILLEPENMLT---EKGDFLNFFYKYSVQTLVAPVILNTIGDRPQNED------- 488
              ..|.:.|::.||: .|.|:   ::.:.::.||:..:..|| .||..:..::..|..
plant   445 --HCQFLEIIRTLLD-ANALSGGAQRANIMDIFYEKHLPELV-DVITASCPEKSSNASEGAARRI 505

  Fly   489 YQTAQLLGIVLDILSFCVEHHSYHIKNFLLQKDLLKRILVLMKSTHTFLVLGALRLLRKIIALKD 553
            :...::|..:.::|.||:...:...|...||.::.:::|.|.:....:||:.|:|.:|.::::.|
plant   506 FTKPEVLLNICELLCFCIMQDASRTKCSFLQNNVTEKVLHLTRRKEKYLVVAAIRFVRTLLSVHD 570

  Fly   554 EFYNRHIVKCNLFAPVVDAFIRNNGRYNLLESAILELFEFIKLEDIRTLCVYFVENFSKIFDEIE 618
            ::...::||.||..|::|.||.|..|||||.||:|:|.|.|:..:...|..|.|:.|.......:
plant   571 DYVQNYVVKNNLLKPIIDVFIANGTRYNLLNSAVLDLLEHIRKGNATLLLKYIVDTFWDQLAPFQ 635

  Fly   619 YVQTFKYLKNRYDQYQDRLKDRDKMENRTDGGLPIIRSGGRFRRDQRQMEEEEEMWFNEEDDFTE 683
            .:.:.:..|.:|:|..:....:    :.:|...|      |.|.|:|.:|:|||.:|||:.|  |
plant   636 CLTSIQAFKVKYEQCLESAGPK----STSDAVDP------RRRVDERALEKEEEDYFNEDSD--E 688

  Fly   684 EIDTYNNVMKSVSEKNGPQTQNQQKSSPPHSTSPHSGLLGSLSTTASSTATSATSGAPVASG--- 745
            |    ::...|.::|..|.:..|::...||              .::..|.|.||.:|.:.|
plant   689 E----DSASASNTQKEKPASNIQKEQPKPH--------------LSNGVAASPTSSSPRSGGLVD 735

  Fly   746 --------------SSSPEAISADEQTQAAVHLAAAALQHHQQQQQQQQQNPFQQQTQPEIAELQ 796
                          ...||| |.||:.:.......:||...:|:..::.:.....:.:...|.|.
plant   736 YEDDEDDEDYKPPPRKQPEA-SEDEEGELLRLKRKSALVEREQEPSKKPRLGKSSKRENVFAVLC 799

  Fly   797 QQLSSVEAPQSQELELSQSAAASASPTSSSSSLEASTSSSSASSSSSSSSSSSPPGSSAA 856
            ..||.......:    |...|.||:.:..:...|.|.||...:||||...:....|.|::
plant   800 STLSHAVLTGKK----SPGPAGSAARSIVAKGAEDSKSSEENNSSSSDDENHKDDGVSSS 855

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
flfl	NP_731849.2	PH-like	8..>66	CDD:302622	29/57 (51%)
flfl	NP_731849.2	SMK-1	169..361	CDD:282636	70/212 (33%)
AT3G06670	NP_001189831.1	SMK-1	167..377	CDD:282636	70/212 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	141	1.000	Domainoid score	I1520
eggNOG	1	0.900	-	-		E1_KOG2175
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	374	1.000	Inparanoid score	I553
OMA	1	1.010	-	-		QHG54949
OrthoDB	1	1.010	-	-		D388216at2759
OrthoFinder	1	1.000	-	-		FOG0001376
OrthoInspector	1	1.000	-	-		otm2943
orthoMCL	1	0.900	-	-		OOG6_101106
Panther	1	1.100	-	-	LDO	PTHR23318
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X869
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840