Protein Alignment flfl and smek1

DIOPT Version :10

• Sequence 1: NP_731849.2
• Gene: flfl / 41675
• FlyBaseID: FBgn0024555
• Length: 980
• Species: Drosophila melanogaster
• Sequence 2: NP_001038274.1
• Gene: smek1 / 558578
• ZFINID: ZDB-GENE-030131-3958
• Length: 818
• Species: Danio rerio
• Alignment Length: 983
• Identity: 456/983 - (46%)
• Similarity: 629/983 - (63%)
• Gaps: 176/983 - (17%)

  Fly     3 TDTRRRVKLYALNAERQWDDRGTGHVSSTYVERLKGISLLVRAESDGSLLLESKIQPDTAYQKQQ 67
            ||||||||:|.||.:|||||||||||||.|||||||:||||||||||||||||||.|:|||||||
Zfish     2 TDTRRRVKVYTLNEDRQWDDRGTGHVSSAYVERLKGMSLLVRAESDGSLLLESKINPNTAYQKQQ 66

  Fly    68 DTLIVWSEGDNFDLALSFQEKAGCDEIWEKICQVQGKDPSVEITQDIVEESEDERFEDMSDTAPP 132
            ||||||||.:|:|||||||||||||||||||||||||||||:|||::::|||:|||:|||  :|.
Zfish    67 DTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVDITQELIDESEEERFDDMS--SPG 129

  Fly   133 IELPPCELSRLEDISETIQSCLSTPLRKEKLSMALESESYIKKLLNLFHVCEDLDNTEGLHHLFE 197
            :|||||||||||:::|.:.|.|.:|||:|||::|||:|.||:|||.||.|||||:|.||||||::
Zfish   130 LELPPCELSRLEEVAELVASSLPSPLRREKLALALENEGYIRKLLELFRVCEDLENREGLHHLYD 194

  Fly   198 IFKNIFLLNKNALFEIMFADDTIFDVVGCLEYDPSVSQPKKHRQYLKQLAKFREAVPIKNLDLLA 262
            |.|.|||||:.||||:||:::.|.||:||||:|||:.||::||::|...|:|:|.:||.:.:|..
Zfish   195 IIKGIFLLNRTALFEVMFSEECIMDVIGCLEFDPSLPQPRRHREFLTTTARFKEVIPISDPELRQ 259

  Fly   263 KIHQTFRVQYIQDIILPTPSVFVEDNMLNTLSSFIFFNKVEIVTMIQDDERYLLDVFAVLTDPTT 327
            |||||:|||||||::||||||| |:|||:||.|||||||||||.|:||||::|.::||.|||..|
Zfish   260 KIHQTYRVQYIQDMVLPTPSVF-EENMLSTLHSFIFFNKVEIVGMLQDDEKFLTELFAQLTDEAT 323

  Fly   328 GDAKRRDTVLFLKEFCNYAQNLQPQGKDSFYKTLTCLGILQALELTLVMNDKKTKSASIDILTAI 392
            .|.||.:.|.||||||.::|.||||.:|:|:|||:.:|||||||:.|.|:|.:.:.|:.||.:.:
Zfish   324 DDDKRHELVNFLKEFCAFSQTLQPQNRDAFFKTLSNMGILQALEVILGMDDVQVRGAATDIFSYL 388

  Fly   393 VEFSPLVVRNYTLNQANRPEVERMLLNIAIEQMLNDSEPELGIAVQLMGIVKILLEPENML---- 453
            ||::|.:||.:.:.::.:.:.:.:|:|:.||.|:.|::||||.||||||:::.|::|||||
Zfish   389 VEYNPSMVREFVMQESQQNDDDILLINLIIEHMICDTDPELGGAVQLMGLLRTLVDPENMLATAN 453

  Fly   454 -TEKGDFLNFFYKYSVQTLVAPVILNTIGDRPQNEDYQTAQLLGIVLDILSFCVEHHSYHIKNFL 517
             |||.:||:||||:.:..|.||::.||..::|..:|:||.|||.:::::|:||||||:|||||::
Zfish   454 KTEKTEFLSFFYKHCMHVLSAPLLANTTEEKPSKDDFQTCQLLALIVELLTFCVEHHTYHIKNYI 518

  Fly   518 LQKDLLKRILVLMKSTHTFLVLGALRLLRKIIALKDEFYNRHIVKCNLFAPVVDAFIRNNGRYNL 582
            :.||:|:|:|||..|.|.||.|.|||.:||||.||||||||:|::..||.|||.||:.|..||||
Zfish   519 INKDILRRVLVLTASQHAFLALCALRFMRKIIGLKDEFYNRYIMRNFLFEPVVKAFLNNGSRYNL 583

  Fly   583 LESAILELFEFIKLEDIRTLCVYFVENFSKIFDEIEYVQTFKYLKNRYDQYQDRLKDRDKMENRT 647
            :.|||:|:||::::||:::|..:.:||:.|..::::||||||.||.||:|.::| :|..|:::..
Zfish   584 INSAIIEMFEYVRVEDVKSLTAHIIENYWKGLEDVDYVQTFKGLKLRYEQQRER-QDNPKLDSMR 647

  Fly   648 DGGLPIIRSGGRFRRDQRQMEEEEEMWFNEEDDFTEEIDTYNNVMKSVSEKNGPQTQNQQKSSPP 712
            .    |:|: .|||||.|.:|:|||||||.:::..|:
Zfish   648 S----ILRN-HRFRRDARTLEDEEEMWFNTDEEDLED---------------------------- 679

  Fly   713 HSTSPHSGLLGSLSTTASSTATSATSGAPVASGSSSPEAISADEQTQAAVHLAAAALQHHQQQQQ 777
                                      |..|...|   :.:..||.....:             .:
Zfish   680 --------------------------GEAVVPPS---DKMKNDEDLMDPI-------------SK 702

  Fly   778 QQQQNPFQQQTQPEIAELQQQLSSVEAPQSQELELSQSAAASASPTSSSSSLEASTSSSSASSSS 842
            ..::...:...:.|:...:..||..::| |.:|..|.|..||.|            |..:||...
Zfish   703 FMERKKLKDSEEKEVLTGKASLSGRQSP-SFKLSFSSSPKASLS------------SPPTASLHP 754

  Fly   843 SSSSSSSPPGSSAAASLCDSATVAAVAASQFLSTIATAMAASVTAAAATNSSPSISPAPAVSSPD 907
            .|..|.|.||:.|.:|
Zfish   755 GSPGSPSSPGTGARSS------------------------------------------------- 770

  Fly   908 IENADAQLPPSDDASSPASGEQDANSTEGTSSEADKTTAKKGLVDYESDSGEDDYEEDEYS--EG 970
                    |||           .|.:|:|         ...|||||..|..||:.|||..|  |.
Zfish   771 --------PPS-----------AAVTTKG---------GLVGLVDYPDDDEEDEDEEDADSKEES 807

  Fly   971 PQAQKRAR 978
            |...|:::
Zfish   808 PPLSKKSK 815

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
flfl	NP_731849.2	PH-like	8..>66	CDD:473070	49/57 (86%)
		PP4R3	169..361	CDD:461435	120/191 (63%)
smek1	NP_001038274.1	PH-like	7..>65	CDD:473070	49/57 (86%)
		PP4R3	166..357	CDD:461435	120/191 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	670..818		50/306 (16%)