Protein Alignment flfl and Ppp4r3b

DIOPT Version :10

• Sequence 1: NP_731849.2
• Gene: flfl / 41675
• FlyBaseID: FBgn0024555
• Length: 980
• Species: Drosophila melanogaster
• Sequence 2: XP_036012096.1
• Gene: Ppp4r3b / 104570
• MGIID: 2144474
• Length: 828
• Species: Mus musculus
• Alignment Length: 827
• Identity: 450/827 - (54%)
• Similarity: 596/827 - (72%)
• Gaps: 77/827 - (9%)

  Fly     3 TDTRRRVKLYALNAERQWDDRGTGHVSSTYVERLKGISLLVRAESDGSLLLESKIQPDTAYQKQQ 67
            :|||||||:|.||.:|||||||||||||||||.|||:||||||||||||||||||.|:|||||||
Mouse     2 SDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNTAYQKQQ 66

  Fly    68 DTLIVWSEGDNFDLALSFQEKAGCDEIWEKICQVQGKDPSVEITQDIVEESEDERFEDMSDTAPP 132
            ||||||||.:|:||||||||||||||||||||||||||||||:|||:::|||:||||:|.:|:..
Mouse    67 DTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEERFEEMPETSHL 131

  Fly   133 IELPPCELSRLEDISETIQSCLSTPLRKEKLSMALESESYIKKLLNLFHVCEDLDNTEGLHHLFE 197
            |:||.||||:||:|::.:.|.||:|:|:|||::|||:|.||||||.||..||:|:||||||||:|
Mouse   132 IDLPACELSKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQACENLENTEGLHHLYE 196

  Fly   198 IFKNIFLLNKNALFEIMFADDTIFDVVGCLEYDPSVSQPKKHRQYLKQLAKFREAVPIKNLDLLA 262
            |.:.|..|||..|||:||:|:.|.||||||||||:::|||:||::|.:.|||:|.:||.:.:|..
Mouse   197 IIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHREFLTKTAKFKEVIPITDSELRQ 261

  Fly   263 KIHQTFRVQYIQDIILPTPSVFVEDNMLNTLSSFIFFNKVEIVTMIQDDERYLLDVFAVLTDPTT 327
            |||||:|||||||||||||||| |:|.|:||:|||||||||||:|:|:||::|.:|||.|||..|
Mouse   262 KIHQTYRVQYIQDIILPTPSVF-EENFLSTLTSFIFFNKVEIVSMLQEDEKFLSEVFAQLTDEAT 325

  Fly   328 GDAKRRDTVLFLKEFCNYAQNLQPQGKDSFYKTLTCLGILQALELTLVMNDKKTKSASIDILTAI 392
            .|.|||:.|.|.||||.::|.||||.:|:|:|||..||||.|||:.:.|:|.:.:||:.||.:.:
Mouse   326 DDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLAKLGILPALEIVMGMDDLQVRSAATDIFSYL 390

  Fly   393 VEFSPLVVRNYTLNQANRPEVERMLLNIAIEQMLNDSEPELGIAVQLMGIVKILLEPENML---- 453
            |||||.:||.:.:.:|.:.:.:.:|:|:.||||:.|::||||.||||||:::.|::|||||
Mouse   391 VEFSPSMVREFVMQEAQQSDDDVLLINVVIEQMICDTDPELGGAVQLMGLLRTLIDPENMLATTN 455

  Fly   454 -TEKGDFLNFFYKYSVQTLVAPVILNTIGDRPQNED----------------------YQTAQLL 495
             |||.:||||||.:.:..|.||::.||..|:.:..|                      |||||||
Mouse   456 KTEKSEFLNFFYNHCMHVLTAPLLTNTSEDKCEKVDFNFFFKDNMLGSNTTNTICPDNYQTAQLL 520

  Fly   496 GIVLDILSFCVEHHSYHIKNFLLQKDLLKRILVLMKSTHTFLVLGALRLLRKIIALKDEFYNRHI 560
            .::|::|:||||||:|||||:::.||||:|:||||.|.||||.|.|||.:|:||.||||||||:|
Mouse   521 ALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGLKDEFYNRYI 585

  Fly   561 VKCNLFAPVVDAFIRNNGRYNLLESAILELFEFIKLEDIRTLCVYFVENFSKIFDEIEYVQTFKY 625
            .|.|||.||::|.:.|..|||||.||::||||||::|||::|..:.||||.|..:.||||||||.
Mouse   586 TKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFYKALESIEYVQTFKG 650

  Fly   626 LKNRYDQYQDRLKDRDKMENRTDGGLPIIRSGGRFRRDQRQMEEEEEMWFNEEDD---------- 680
            ||.:|:|.:||       :|:....:|.|....|||||.:.:||:|||||||:||
Mouse   651 LKTKYEQEKDR-------QNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNEDDDEEGKAVITPV 708

  Fly   681 ---FTEE--IDTYNNVMKSVSEKNGPQTQNQQKSSP--------PHS------------------ 714
               .||:  .|:|...|::...|.....:|..|.:.        .||
Mouse   709 EKSKTEDDFPDSYEKFMETKKAKESEDKENLPKRASSGGFKFTFSHSPSATNGTNSTNSKSVVSQ 773

  Fly   715 TSPHSGLLGSLSTTASSTATSATSGAPVASGSSSPEAISADEQTQAA 761
            |:|.|..:.|..||:.:|:.:||.|..|.. ...|:....||:.:::
Mouse   774 TTPASSNVASSKTTSLATSVTATKGNLVGL-VDYPDDEEEDEEEESS 819

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
flfl	NP_731849.2	PH-like	8..>66	CDD:473070	49/57 (86%)
		PP4R3	169..361	CDD:461435	123/191 (64%)
Ppp4r3b	XP_036012096.1	PH-like	7..>65	CDD:473070	49/57 (86%)
		PP4R3	168..359	CDD:461435	123/191 (64%)