Protein Alignment flfl and Ppp4r3cl3

DIOPT Version :10

• Sequence 1: NP_731849.2
• Gene: flfl / 41675
• FlyBaseID: FBgn0024555
• Length: 980
• Species: Drosophila melanogaster
• Sequence 2: XP_038956280.1
• Gene: Ppp4r3cl3 / 100909486
• RGDID: 6503220
• Length: 795
• Species: Rattus norvegicus
• Alignment Length: 745
• Identity: 340/745 - (45%)
• Similarity: 480/745 - (64%)
• Gaps: 46/745 - (6%)

  Fly     9 VKLYALNAERQWDDRGTGHVSSTYVERLKGISLLVRAESDGSLLLESKIQPDTAYQKQQDTLIVW 73
            ||:|.:..::||.|.|||.:||.|:|..:|..|||.:|.|||.::|.||.|:..||||.: :|:|
  Rat    13 VKVYVMVEDKQWKDIGTGQISSKYIEWHQGACLLVHSELDGSPIMECKILPNVPYQKQGE-VIIW 76

  Fly    74 SEGDNFDLALSFQEKAGCDEIWEKICQVQGKDPSVEITQDIVEESEDERFEDMSDTAPPIELPPC 138
            ||..|..:|:.|.|..||.||||.|||||||||.||||||:.::.|.  |||:|.:...:|:...
  Rat    77 SEAKNHGMAIHFLEPKGCQEIWEDICQVQGKDPKVEITQDLTDDLES--FEDLSLSWKRVEMSNY 139

  Fly   139 ELSRLEDISETIQSCLSTPLRKEKLSMALESESYIKKLLNLFHVCEDLDNTEGLHHLFEIFKNIF 203
            ||..|::|:|........|..||:|::.||:|.||||||.||..||.|.|.|||::|..|.|.|.
  Rat   140 ELDTLKNIAELFPFVFEMPNHKERLAVVLENEGYIKKLLQLFKTCEKLKNMEGLYYLHNIIKGIL 204

  Fly   204 LLNKNALFEIMFADDTIFDVVGCLEYDPSVSQPKKHRQYLKQLAKFREAVPIKNLDLLAKIHQTF 268
            .||...||.|||:|:...||||||||||::.||||:||:|.|.|||:|.:||.:..|..||.:|:
  Rat   205 FLNDTHLFNIMFSDEFFMDVVGCLEYDPALDQPKKYRQFLTQNAKFKEVMPITHSQLRKKIQETY 269

  Fly   269 RVQYIQDIILPTPSVFVEDNMLNTLSSFIFFNKVEIVTMIQDDERYLLDVFAVLTDPTTGDAKRR 333
            |:|||.||:|||||:| |.|:|:.|::.|||||:||:||:|:||.:||::||.|.|.|.||.:|.
  Rat   270 RMQYIHDIVLPTPSIF-EGNLLSDLTTMIFFNKIEIITMLQEDEHFLLEIFAQLKDNTVGDERRH 333

  Fly   334 DTVLFLKEFCNYAQNLQPQGKDSFYKTLTCLGILQALELTLVMNDKKTKSASIDILTAIVEFSPL 398
            :.:||.||||.:|:.|..|.|:...|||..|||:.||::.:.|:|.:.:.|::::...:||:||.
  Rat   334 ELLLFFKEFCAFAKTLHSQKKNMLLKTLIKLGIMSALKVVVHMHDYQIQVAALELFACLVEYSPR 398

  Fly   399 VVRNYTLNQA-NRPEVERMLLNIAIEQMLNDSEPELGIAVQLMGIVKILLEPENMLT-----EKG 457
            :||.|.:.:| |..:.:.:||||.|.||:.||:||....:.|..::..||.||||..     |:.
  Rat   399 LVRAYAMQEAQNSEDNDDLLLNIMINQMICDSDPEFSRGIILTAVLHDLLNPENMRVTVNGYERK 463

  Fly   458 DFLNFFYKYSVQTLVAPVILNTI-GDRPQN------EDYQTAQLLGIVLDILSFCVEHHSYHIKN 515
            .|||||||..::.|:||::..|: .|...|      ::||.|||||.:|:||:|||::||.:||:
  Rat   464 GFLNFFYKRCMRNLIAPILSTTVENDSNDNRGYICPDNYQNAQLLGAILEILTFCVQNHSMYIKH 528

  Fly   516 FLLQKDLLKRILVLMKSTHTFLVLGALRLLRKIIALKDEFYNRHIVKCNLFAPVVDAFIRNNGRY 580
            :::..:||.||||||.|.||||:|.|:|.:||:|.|||:.|:.:|:|.|||.|||:||:.|..||
  Rat   529 YIMSNNLLSRILVLMSSKHTFLILCAVRFMRKMIGLKDKIYSLYIIKENLFEPVVNAFMYNGHRY 593

  Fly   581 NLLESAILELFEFIKLEDIRTLCVYFVENFSKIFDEIEYVQTFKYLKNRYDQYQDRLKDRDKMEN 645
            |:|.|||:||||||:.|:|::|....||.|...|:.||||||||.||.:|::        :|.::
  Rat   594 NMLNSAIIELFEFIRKENIKSLIANIVEKFFMAFESIEYVQTFKGLKTKYEE--------EKKKS 650

  Fly   646 RTDGGLP-IIRS-------------GGRFRRDQRQMEEEEEMWFNEE------DDFTEEIDTYNN 690
            ||...|| ||.|             |......:|..|||||....||      .:||.:.|.:..
  Rat   651 RTRRNLPNIIYSKIYCGHTKDIELKGKADTSCRRITEEEEEEEGGEEGILPMGSNFTGKCDIFME 715

  Fly   691 VMKSVSEKNGPQTQNQQKSSPPHSTSPHSG 720
            : |..:|......:.::|||......|.:|
  Rat   716 I-KGKNESENKIERTKRKSSEAFENFPSNG 744

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
flfl	NP_731849.2	PH-like	8..>66	CDD:473070	27/56 (48%)
		PP4R3	169..361	CDD:461435	105/191 (55%)
Ppp4r3cl3	XP_038956280.1	PH-like	10..>75	CDD:473070	29/62 (47%)
		PP4R3	170..361	CDD:461435	105/191 (55%)