DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment flfl and LOC100909486

DIOPT Version :9

Sequence 1:	NP_731849.2	Gene:	flfl / 41675	FlyBaseID:	FBgn0024555	Length:	980	Species:	Drosophila melanogaster
Sequence 2:	XP_038956280.1	Gene:	LOC100909486 / 100909486	RGDID:	6503220	Length:	795	Species:	Rattus norvegicus

Alignment Length:	745	Identity:	340/745 - (45%)
Similarity:	480/745 - (64%)	Gaps:	46/745 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VKLYALNAERQWDDRGTGHVSSTYVERLKGISLLVRAESDGSLLLESKIQPDTAYQKQQDTLIVW 73
            ||:|.:..::||.|.|||.:||.|:|..:|..|||.:|.|||.::|.||.|:..||||.: :|:|
  Rat    13 VKVYVMVEDKQWKDIGTGQISSKYIEWHQGACLLVHSELDGSPIMECKILPNVPYQKQGE-VIIW 76

  Fly    74 SEGDNFDLALSFQEKAGCDEIWEKICQVQGKDPSVEITQDIVEESEDERFEDMSDTAPPIELPPC 138
            ||..|..:|:.|.|..||.||||.|||||||||.||||||:.::.|.  |||:|.:...:|:...
  Rat    77 SEAKNHGMAIHFLEPKGCQEIWEDICQVQGKDPKVEITQDLTDDLES--FEDLSLSWKRVEMSNY 139

  Fly   139 ELSRLEDISETIQSCLSTPLRKEKLSMALESESYIKKLLNLFHVCEDLDNTEGLHHLFEIFKNIF 203
            ||..|::|:|........|..||:|::.||:|.||||||.||..||.|.|.|||::|..|.|.|.
  Rat   140 ELDTLKNIAELFPFVFEMPNHKERLAVVLENEGYIKKLLQLFKTCEKLKNMEGLYYLHNIIKGIL 204

  Fly   204 LLNKNALFEIMFADDTIFDVVGCLEYDPSVSQPKKHRQYLKQLAKFREAVPIKNLDLLAKIHQTF 268
            .||...||.|||:|:...||||||||||::.||||:||:|.|.|||:|.:||.:..|..||.:|:
  Rat   205 FLNDTHLFNIMFSDEFFMDVVGCLEYDPALDQPKKYRQFLTQNAKFKEVMPITHSQLRKKIQETY 269

  Fly   269 RVQYIQDIILPTPSVFVEDNMLNTLSSFIFFNKVEIVTMIQDDERYLLDVFAVLTDPTTGDAKRR 333
            |:|||.||:|||||:| |.|:|:.|::.|||||:||:||:|:||.:||::||.|.|.|.||.:|.
  Rat   270 RMQYIHDIVLPTPSIF-EGNLLSDLTTMIFFNKIEIITMLQEDEHFLLEIFAQLKDNTVGDERRH 333

  Fly   334 DTVLFLKEFCNYAQNLQPQGKDSFYKTLTCLGILQALELTLVMNDKKTKSASIDILTAIVEFSPL 398
            :.:||.||||.:|:.|..|.|:...|||..|||:.||::.:.|:|.:.:.|::::...:||:||.
  Rat   334 ELLLFFKEFCAFAKTLHSQKKNMLLKTLIKLGIMSALKVVVHMHDYQIQVAALELFACLVEYSPR 398

  Fly   399 VVRNYTLNQA-NRPEVERMLLNIAIEQMLNDSEPELGIAVQLMGIVKILLEPENMLT-----EKG 457
            :||.|.:.:| |..:.:.:||||.|.||:.||:||....:.|..::..||.||||..     |:.
  Rat   399 LVRAYAMQEAQNSEDNDDLLLNIMINQMICDSDPEFSRGIILTAVLHDLLNPENMRVTVNGYERK 463

  Fly   458 DFLNFFYKYSVQTLVAPVILNTI-GDRPQN------EDYQTAQLLGIVLDILSFCVEHHSYHIKN 515
            .|||||||..::.|:||::..|: .|...|      ::||.|||||.:|:||:|||::||.:||:
  Rat   464 GFLNFFYKRCMRNLIAPILSTTVENDSNDNRGYICPDNYQNAQLLGAILEILTFCVQNHSMYIKH 528

  Fly   516 FLLQKDLLKRILVLMKSTHTFLVLGALRLLRKIIALKDEFYNRHIVKCNLFAPVVDAFIRNNGRY 580
            :::..:||.||||||.|.||||:|.|:|.:||:|.|||:.|:.:|:|.|||.|||:||:.|..||
  Rat   529 YIMSNNLLSRILVLMSSKHTFLILCAVRFMRKMIGLKDKIYSLYIIKENLFEPVVNAFMYNGHRY 593

  Fly   581 NLLESAILELFEFIKLEDIRTLCVYFVENFSKIFDEIEYVQTFKYLKNRYDQYQDRLKDRDKMEN 645
            |:|.|||:||||||:.|:|::|....||.|...|:.||||||||.||.:|::        :|.::
  Rat   594 NMLNSAIIELFEFIRKENIKSLIANIVEKFFMAFESIEYVQTFKGLKTKYEE--------EKKKS 650

  Fly   646 RTDGGLP-IIRS-------------GGRFRRDQRQMEEEEEMWFNEE------DDFTEEIDTYNN 690
            ||...|| ||.|             |......:|..|||||....||      .:||.:.|.:..
  Rat   651 RTRRNLPNIIYSKIYCGHTKDIELKGKADTSCRRITEEEEEEEGGEEGILPMGSNFTGKCDIFME 715

  Fly   691 VMKSVSEKNGPQTQNQQKSSPPHSTSPHSG 720
            : |..:|......:.::|||......|.:|
  Rat   716 I-KGKNESENKIERTKRKSSEAFENFPSNG 744

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
flfl	NP_731849.2	PH-like	8..>66	CDD:302622	27/56 (48%)
flfl	NP_731849.2	SMK-1	169..361	CDD:282636	105/191 (55%)
LOC100909486	XP_038956280.1	PH-like	10..>75	CDD:418428	29/62 (47%)
LOC100909486	XP_038956280.1	SMK-1	170..361	CDD:398462	105/191 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D261288at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010