Protein Alignment omd and ints-5

DIOPT Version :9

• Sequence 1: NP_001262542.1
• Gene: omd / 41674
• FlyBaseID: FBgn0038168
• Length: 994
• Species: Drosophila melanogaster
• Sequence 2: NP_507625.2
• Gene: ints-5 / 180207
• WormBaseID: WBGene00013075
• Length: 1057
• Species: Caenorhabditis elegans
• Alignment Length: 1120
• Identity: 198/1120 - (17%)
• Similarity: 367/1120 - (32%)
• Gaps: 344/1120 - (30%)

  Fly    32 LIKLALGFLEELPATRDIVFEYFALLAEISVQLYVSPEMADPKTGMPVSQVKLAGNRQQQQRAPE 96
            |:|.|:......||:|..||.|..||...|...:.:.:    :....||.:.:. |....:....
 Worm    61 LVKPAIDVFRAFPASRPTVFHYTGLLIHESAHHWFNAQ----ENVQQVSNITIV-NEATCELLDF 120

  Fly    97 YEAF-------NLVKTALQSLVWKGPPAWSPLIANWSLELVAKLSDKYTQRRMTITASCN----- 149
            |..|       :.::..||                |..|:.::||.|...|...:.|..|
 Worm   121 YMKFFAETDGNSGLEECLQ----------------WLCEICSELSSKNAGRPAMLPAQQNAEILQ 169

  Fly   150 YWLECSAMHGLMTLINSCFRKLTQPEEEACVEIMLNAFHRFPMTFDWIVARLGGCFPYKIIMQIL 214
            .|.....:..|::|::.|...........|:..:..| .|....|.||...:.......||..:|
 Worm   170 IWKSNDVIDKLLSLLSICVTSSLAQNSVGCMRALFEA-SRHGQHFSWIWLHIATLLQGSIITHLL 233

  Fly   215 QCGIKRF------------------------VDDYRCHLDSEAGILDYMTSCHEQHLRAAFREML 255
            :.|.::|                        ..:|.....:.:.:.:::.......|:.|..:::
 Worm   234 ESGAEQFRTYVIEISSRKTVQTGGPAVLNIIQTEYEHKFRAISDVFNFLMQKRNPELQEAVSQLI 298

  Fly   256 ------------------REGFA--------PKKPLDVAV-------VPF--------------- 272
                              |.|||        ..|.|.:.|       .||
 Worm   299 VDSLDFKPAAGRGGGSVNRLGFAFFFKLVTCSLKTLQILVNTNCHLITPFNVIRAIRQVQTVEKS 363

  Fly   273 -LLITTNYSDTILQSLVNVLVE--------IYTEDMCEVIVQKAPLWLSN---------KMFAGM 319
             :|....:||.|.|     :||        |..|.:.|::...|.....|         |:.|..
 Worm   364 LILPAITFSDFIKQ-----IVEDVDPITHGIIFELLVELVYNPAVFEGENLPEFRESNEKIRADC 423

  Fly   320 QPTLNNAVLRL----NERG---ATLLLTAAKM---AEKYVWCQDFLDNSMQELEQWVLNQRNFPL 374
            .|.|:..:.|:    :..|   .:.|..|.::   .||..:..|...|....|:......|:...
 Worm   424 FPVLDVMISRIIRIAHSAGGYKCSSLHPAIQLYSSGEKLQFIIDSAKNCTDNLQMTSSIIRHLHA 488

  Fly   375 LADLAYEETK--YMLWKSCLSTNLFEQQTAVRLLLVVSSQHPNIYYQTISQLLKKSYAQNPNGIG 437
            :: :|::|:|  .:..:..::|:..:.:....|:..:|:..|  :|   .|:|.|.:|:
 Worm   489 IS-IAFDESKAAEIALRFLMTTDFGDSKKLEILMAYLSATVP--FY---PQMLAKMWAE------ 541

  Fly   438 ALIRLLGGQSGMVNFPGFTPGFKMVLEDITLDVQVNNRLPVPPGTPTEAFNTFSNLNILARMHKS 502
                 .||...::.| .|.|...:..:.|.:.:.:.:.           |.|..:..:.......
 Worm   542 -----FGGLRELIAF-SFDPESPLKRDSIHVHMNLLHN-----------FRTIFDWELHTAPAAP 589

  Fly   503 KNVAPYIK---AQHLNQALNECLPKILQIFDC-------------TVNKLVLRI----------D 541
            ||...:.|   .||:...||..|...::|  |             |:.:||.::          .
 Worm   590 KNSYGFWKLYPGQHIGSVLNTILTNTVKI--CWELQEANKLSEVITIYRLVTKLIEGVCQSNSTG 652

  Fly   542 RDAAERIADKFRAQQSKNSN--------------------NNNELCNGKDYGKRTKLEPGEDKVD 586
            |.||:        |..|||.                    .|..|..|:|.       |....:.
 Worm   653 RTAAD--------QNVKNSRKMVITLSQMYKLMAQFAILLKNALLLVGRDL-------PDGIVIF 702

  Fly   587 DEDATRMRLAHLIVDLLNNIEAGSRTTVLRTPLVLKLATLSVKYFFVG--LTEKTVIRRAAASHR 649
            :|    :|...|.....|:::          |.:.:.:.:.|:.|...  ...|.:.......|.
 Worm   703 EE----LRAQCLYFLFGNHLD----------PQLSRFSPVFVQIFVQSCYADAKKLFHEPIIDHG 753

  Fly   650 SYTLLQRQCSARKIARTVCLRELVERALFYHGHLLGQLEVYQLDELEIPEHEHLILQNLHTSSGA 714
            ...||.   ..:.:.|.:.::|||:          |...:.||..|::                .
 Worm   754 LEQLLD---ETQGLGRILDMQELVD----------GPSVIGQLKSLKM----------------R 789

  Fly   715 NSNRSVLHSGIIGRGLRPVL--PPSERNCDAEKQA-LYLKALNACCADLEKPNNVEGYSLVSLLL 776
            :|..::||:|.:.|  |.:|  |.:..|.:|.::. :.|.|:...|...:....:.....::..|
 Worm   790 DSALAMLHTGQLKR--RRLLEDPVTVENENATQRVYVVLDAIRLMCTSGKLEIRIGCSKHLAQAL 852

  Fly   777 VELVSTDVMYNGLPFPDEEFTRVTMERDMLIRRAFINSPVLWAVLGLIAGHRPALCYSSVLLRAL 841
            ::.:..|.:.:.:.|.:.:.....:.|.:.|.:....||....:|.::|..| :..|...::::.
 Worm   853 LQTICKDSLMSDMRFDEWDSEAEFIHRHVEIAQRIARSPFSDGILRILAETR-SFAYCLPIMKSK 916

  Fly   842 CATCLHHWRGKNVNRFQPTAANDELMLCTKKMLQ---LLAMSQLIPP----PLTNLHLIIEHFES 899
            .|..|:     :..:|....|..|   .|::.||   .||....|.|    |:.:|    |.|.:
 Worm   917 LAVLLN-----DTEKFPEHVAISE---PTRQKLQNWVFLAQKGGILPGRLAPICDL----EQFST 969

  Fly   900 A-EIALLLRECIWNYLKDHVPSPALFHVDNNGLHWRNTNTQLAKVPPQYVDPLRHLMQRKLSTLG 963
            . |..|:|.| ||.:.                                   .:|.|....:.|
 Worm   970 CHETHLMLVE-IWRFF-----------------------------------VVRQLNTATIDT-- 996

  Fly   964 PHYHQMFIMGELMEG 978
              ||...:.|::.||
 Worm   997 --YHMEILRGDVDEG 1009

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
omd	NP_001262542.1	INTS5_N	4..221	CDD:291503	41/200 (21%)
		INTS5_C	229..962	CDD:291504	149/869 (17%)
ints-5	NP_507625.2	INTS5_N	43..242	CDD:373329	42/202 (21%)
		INTS5_C	<798..984	CDD:373330	43/201 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163601
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46681
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108361
Panther	1	1.100	-	-	LDO	PTHR31697
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4370
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.970