DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lkb1 and SnRK1.3

DIOPT Version :9

Sequence 1:	NP_001163606.1	Gene:	Lkb1 / 41673	FlyBaseID:	FBgn0038167	Length:	567	Species:	Drosophila melanogaster
Sequence 2:	NP_198760.1	Gene:	SnRK1.3 / 833940	AraportID:	AT5G39440	Length:	494	Species:	Arabidopsis thaliana

Alignment Length:	290	Identity:	104/290 - (35%)
Similarity:	158/290 - (54%)	Gaps:	19/290 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   164 KSIKMVGKYIMGDVLGEGSYGKVKEAMNSENLCRLAVKILTKRKLRRIPNGEQNVTREIALLKQL 228
            |.:.::..|.:|..||.||:.|||.|::.....::|:|||.:.|::.: ..|..|.|||.:|:.|
plant    11 KLVSILPNYRIGKTLGHGSFAKVKLALHVATGHKVAIKILNRSKIKNM-GIEIKVQREIKILRFL 74

  Fly   229 KHRHVVELVDVLYNEEKQKMYLVMEYCVGGLQEMIDYQPDK-RMPLFQAHGYFKQLVDGLEYLHS 292
            .|.|::...:|:  |....:|:||||...|  |:.||..:| ::...:|...|:|::.|:||.|.
plant    75 MHPHIIRQYEVI--ETPNDIYVVMEYVKSG--ELFDYIVEKGKLQEDEARHLFQQIISGVEYCHR 135

  Fly   293 CRVIHKDIKPGNLLLSLDQTLKISDFGVAEQLDLFAPDDTCTTGQGSPAFQPPEIANGHETFAGF 357
            ..::|:|:||.|:||.....:||.|||::   ::........|..|||.:..||:.:|..  .|.
plant   136 NMIVHRDLKPENVLLDSQCNIKIVDFGLS---NVMHDGHFLKTSCGSPNYAAPEVISGKP--YGP 195

  Fly   358 KVDIWSSGVTLYNLATGQYPFEGDNIYRLLENIGRGQWEAPAWLYEMDADFANLILGMLQADPSK 422
            .|||||.||.||.|..|..||:.:||..:.|.|.||.:..|..|.....|   ||..||..||:.
plant   196 DVDIWSCGVILYALLCGTLPFDDENIPNVFEKIKRGMYTLPNHLSHFARD---LIPRMLMVDPTM 257

  Fly   423 RLSLQEIRHDTWFRS-APVKTGPPIPIPPL 451
            |:|:.|||...||.: .|:.    :.||||
plant   258 RISITEIRQHPWFNNHLPLY----LSIPPL 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lkb1	NP_001163606.1	S_TKc	172..435	CDD:214567	96/263 (37%)
Lkb1	NP_001163606.1	STKc_LKB1	178..435	CDD:271021	94/257 (37%)
SnRK1.3	NP_198760.1	STKc_AMPK_alpha	16..270	CDD:270981	96/266 (36%)
		UBA_SnRK1_plant	292..332	CDD:270520
		AMPKA_C	388..491	CDD:213378
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910