DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lkb1 and CIPK25

DIOPT Version :9

Sequence 1:	NP_001163606.1	Gene:	Lkb1 / 41673	FlyBaseID:	FBgn0038167	Length:	567	Species:	Drosophila melanogaster
Sequence 2:	NP_568466.1	Gene:	CIPK25 / 832582	AraportID:	AT5G25110	Length:	488	Species:	Arabidopsis thaliana

Alignment Length:	298	Identity:	97/298 - (32%)
Similarity:	169/298 - (56%)	Gaps:	18/298 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   150 NRVDSQDIIYQQKKKSIKMVGKYIMGDVLGEGSYGKV---KEAMNSENLCRLAVKILTKRKLRRI 211
            :|..|...:.:::::...:..||.||.:||:|::|||   ||....|:   :|:||:.|.:::|.
plant    21 SRYQSAPTMEEEQQQLRVLFAKYEMGRLLGKGTFGKVYYGKEITTGES---VAIKIINKDQVKRE 82

  Fly   212 PNGEQNVTREIALLKQLKHRHVVELVDVLYNEEKQKMYLVMEYCVGGLQEMIDYQPDKRMPLFQA 276
            ...|| :.|||::::.::|.::|||.:|:  ..|.|::.:|||..||  |:.......::....|
plant    83 GMMEQ-IKREISIMRLVRHPNIVELKEVM--ATKTKIFFIMEYVKGG--ELFSKIVKGKLKEDSA 142

  Fly   277 HGYFKQLVDGLEYLHSCRVIHKDIKPGNLLLSLDQTLKISDFGVAEQLDLFAPDDTCTTGQGSPA 341
            ..||:||:..:::.||..|.|:|:||.|||:..:..||:||||::...:....|....|..|:||
plant   143 RKYFQQLISAVDFCHSRGVSHRDLKPENLLVDENGDLKVSDFGLSALPEQILQDGLLHTQCGTPA 207

  Fly   342 FQPPEIANGHETFAGFKVDIWSSGVTLYNLATGQYPFEGDNIYRLLENIGRGQWEAPAWLYEMDA 406
            :..||:.. .:.:.|.|.||||.|:.||.|..|..||:.:|:.::...|.:.::|.|.|   ...
plant   208 YVAPEVLR-KKGYDGAKGDIWSCGIILYVLLAGFLPFQDENLMKMYRKIFKSEFEYPPW---FSP 268

  Fly   407 DFANLILGMLQADPSKRLSLQEIRHDTWFR---SAPVK 441
            :...||..:|..||:||:|:..|....|||   ::|::
plant   269 ESKRLISKLLVVDPNKRISIPAIMRTPWFRKNINSPIE 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lkb1	NP_001163606.1	S_TKc	172..435	CDD:214567	90/265 (34%)
Lkb1	NP_001163606.1	STKc_LKB1	178..435	CDD:271021	87/259 (34%)
CIPK25	NP_568466.1	STKc_SnRK3	42..296	CDD:271133	91/265 (34%)
		S_TKc	43..297	CDD:214567	90/265 (34%)
		CIPK_C	342..455	CDD:213380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910