Protein Alignment Lkb1 and sik1

DIOPT Version :9

• Sequence 1: NP_001163606.1
• Gene: Lkb1 / 41673
• FlyBaseID: FBgn0038167
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: NP_001119855.1
• Gene: sik1 / 553465
• ZFINID: ZDB-GENE-030131-9446
• Length: 811
• Species: Danio rerio
• Alignment Length: 364
• Identity: 107/364 - (29%)
• Similarity: 176/364 - (48%)
• Gaps: 56/364 - (15%)

  Fly   169 VGKYIMGDVLGEGSYGKVKEAMNSEN-----------LCRLAVKILTKRKLRRIPNGEQNVTREI 222
            ||.|.:...||:|::..||.|.:...           ..::|:||:.|.:|...  ..:.:.||:
Zfish    23 VGFYEIIRTLGKGNFAVVKLARHKVTKTQAITTFYFIFMQVAIKIIDKTRLNSA--NLEKIYREV 85

  Fly   223 ALLKQLKHRHVVELVDVLYNEEKQKMYLVMEYCVGGLQEMIDY-QPDKRMPLFQAHGYFKQLVDG 286
            .::|.|.|.|:::|..|:  |.|..:|:|.||...|  ||.|| ..:.||...:|...|.|::..
Zfish    86 QIMKLLNHPHIIKLYQVM--ETKDMLYIVTEYAKNG--EMFDYLTSNGRMSENEARKKFWQILTA 146

  Fly   287 LEYLHSCRVIHKDIKPGNLLLSLDQTLKISDFGVAEQLDLFAPDDTCTTGQGSPAFQPPEIANGH 351
            ::|.|...::|:|:|..||||..:..:|::|||..   :.:...:..:|..|||.:..||:..|.
Zfish   147 VDYCHRHHIVHRDLKTENLLLDANMNIKLADFGFG---NFYNAGEPLSTWCGSPPYAAPEVFEGK 208

  Fly   352 ETFAGFKVDIWSSGVTLYNLATGQYPFEGDNIYRLLENIGRGQWEAPAWLYEMDADFANLILGML 416
            | :.|.::||||.||.||.|..|..||:||::..|.:.:..|::..|   :.|..|..|||..||
Zfish   209 E-YEGPQLDIWSLGVVLYVLVCGSLPFDGDSLPALRQRVTEGRFRIP---FFMSQDCENLIRKML 269

  Fly   417 QADPSKRLSLQEIRHDTWF---RSAPVKT----------------GPPIPIPPLKG-DKYRNSTV 461
            ..||:||:::.:|:...|.   .|||.:|                .|.:.|....| |:.|....
Zfish   270 VVDPAKRITIAQIKQHRWMLADPSAPHQTLSLSLTDYNSNLGDYSEPVLGIMQTLGIDRQRTVES 334

  Fly   462 IPYLEAYHYGTQEEDVYF------TEHDVNQELARQAAA 494
            :......|:..    :|:      .||. :|:::||..|
Zfish   335 LQNSSYNHFSA----IYYLLLERVKEHR-SQQISRQCGA 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lkb1	NP_001163606.1	S_TKc	172..435	CDD:214567	87/274 (32%)
		STKc_LKB1	178..435	CDD:271021	86/268 (32%)
sik1	NP_001119855.1	STKc_SIK	25..288	CDD:270973	87/275 (32%)
		S_TKc	26..288	CDD:214567	87/274 (32%)
		UBA_SIK1	309..358	CDD:270591	8/52 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910