Protein Alignment Lkb1 and PhKgamma

DIOPT Version :9

• Sequence 1: NP_001163606.1
• Gene: Lkb1 / 41673
• FlyBaseID: FBgn0038167
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: NP_511129.3
• Gene: PhKgamma / 32120
• FlyBaseID: FBgn0011754
• Length: 560
• Species: Drosophila melanogaster
• Alignment Length: 440
• Identity: 119/440 - (27%)
• Similarity: 201/440 - (45%)
• Gaps: 70/440 - (15%)

  Fly   153 DSQDIIYQQKKKSIKMVGKYIMGDVLGEGSYGKVKEAMNSENLCRLAVKILTKRKLRRIPNGEQN 217
            |.:|.:...|..:.....||...::||.|....|:..:..|.....|.||:.......  :||.|
  Fly     4 DEEDDLLPDKDAAKGFYAKYEPKEILGRGISSTVRRCIEKETGKEFAAKIIDLGATTE--SGETN 66

  Fly   218 ------VTR-EIALLKQ-LKHRHVVELVDVLYNEEKQKMYLVMEYCVGGLQEMIDY------QPD 268
                  .|| ||::|:| :.|.::::|.||.  |....::||.|.|..|  |:.||      ..:
  Fly    67 PYHMLEATRQEISILRQVMGHPYIIDLQDVF--ESDAFVFLVFELCPKG--ELFDYLTSVVTLSE 127

  Fly   269 KRMPLFQAHGYFKQLVDGLEYLHSCRVIHKDIKPGNLLLSLDQTLKISDFGVAEQLDLFAPDDTC 333
            |:     .....:|:.:|:||:|:..::|:|:||.|:||..:..:||:|||.|:||.   ..:..
  Fly   128 KK-----TRTIMRQIFEGVEYIHAKSIVHRDLKPENILLDENHNVKITDFGFAKQLQ---EGEKL 184

  Fly   334 TTGQGSPAFQPPEI--ANGHETFAGF--KVDIWSSGVTLYNLATGQYPFEGDNIYRLLENIGRGQ 394
            |...|:|.:..||.  .|..|...|:  :||||:.||.::.|..|..||.......:|.||..|:
  Fly   185 TNLCGTPGYLAPETLKCNMFEGSPGYSQEVDIWACGVIMFTLLVGCPPFWHRKQMVMLRNIMEGK 249

  Fly   395 WE--APAWLYEMDADFANLILGMLQADPSKRLSLQEIRHDTWFRSAPVKTGPPIPIPPLKGDKYR 457
            :.  :|.|. ::..|..:||...|..|||:|::::|:....:|....:......|.||:...:..
  Fly   250 YSFTSPEWA-DISEDPKDLIRKCLVVDPSQRITVKEVLRHPFFNQMVLMGDRRHPAPPIAPAQTN 313

  Fly   458 NSTVI-PYLEAYHYGTQEED-------VYFTEHDVNQELARQAAAAASEIR------AKQSAAAL 508
            :..:: |...:|.:|.....       :|         .|.|::.:::.:|      |..|||:
  Fly   314 SRHLLQPEASSYRFGQLNSSCAGAPNYLY---------CAPQSSYSSNRMRDGALDDAGASAAS- 368

  Fly   509 AACHTYEPPSTSAAAASNSLGNGSREEAPVKKKGSALKRRA--KKLTSCI 556
            |.||...|.:.|.:.|:|:..|.|         .|||...:  |.||:.:
  Fly   369 ATCHVMSPSNASNSYATNTTANTS---------NSALASASSHKTLTAMV 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lkb1	NP_001163606.1	S_TKc	172..435	CDD:214567	85/282 (30%)
		STKc_LKB1	178..435	CDD:271021	84/276 (30%)
PhKgamma	NP_511129.3	STKc_PhKG	19..291	CDD:270995	86/286 (30%)
		S_TKc	23..291	CDD:214567	85/282 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452309
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930