Protein Alignment Lkb1 and ckk-1

DIOPT Version :9

• Sequence 1: NP_001163606.1
• Gene: Lkb1 / 41673
• FlyBaseID: FBgn0038167
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: NP_001021153.1
• Gene: ckk-1 / 182278
• WormBaseID: WBGene00000518
• Length: 541
• Species: Caenorhabditis elegans
• Alignment Length: 524
• Identity: 148/524 - (28%)
• Similarity: 223/524 - (42%)
• Gaps: 128/524 - (24%)

  Fly   119 DDQPHPQVTWLDDDEIETLDRVT-LDMGNMFFNRVDSQDI------------------------- 157
            ||.|.|..|........|:||.: |...:|...:.|:..:
 Worm    36 DDSPGPSSTVSTMTTTGTVDRRSLLSAASMVRQQSDTTGVRRLVRARAVQEDDEAGPHSSNNLAA 100

  Fly   158 ---------------IYQQKKKSIKMVGKYIMGDVLGEGSYGKVKEAMNSENLCRLAVKILTKRK 207
                           :.||:.:|...:.:|.:.:.:|:||||.||.|.|.|:....|:|:|.|.|
 Worm   101 TMSPNLSRPTRYVKSVSQQRSESYIQLNQYRLMEEIGQGSYGIVKLAYNEEDKNLYALKVLDKMK 165

  Fly   208 L------------RR---------IPNGEQNVTREIALLKQLKHRHVVELVDVLYNEEKQKMYLV 251
            |            ||         :.|..|.|.:|||:||:|.|.:||:||:||.:.....:|:|
 Worm   166 LLKNFACFRQPPPRRNKENAAPSVLRNPLQLVQKEIAILKKLSHPNVVKLVEVLDDPNDNYLYMV 230

  Fly   252 MEYCVGGLQEMIDYQPDKRMPLFQAHGYFKQLVDGLEYLHSCRVIHKDIKPGNLLLSLDQTLKIS 316
            .|:...|  .:::...||.:....|..||:..:.||||||..:::|:||||.|||||....:||:
 Worm   231 FEFVEKG--SILEIPTDKPLDEDTAWSYFRDTLCGLEYLHYQKIVHRDIKPSNLLLSDIGQVKIA 293

  Fly   317 DFGVA---EQLDLFAPDDTCTTGQGSPAFQPPE-IANG-HETFAGFKVDIWSSGVTLYNLATGQY 376
            ||||:   |.:|.|.....     |:|||..|| :..| :..::|...||||.|:|||....|..
 Worm   294 DFGVSCEFEGIDAFLSGTA-----GTPAFMAPEALTEGANHFYSGRAQDIWSLGITLYAFVIGTV 353

  Fly   377 PFEGDNIYRLLENIGRGQW---EAPAWLYEMDADFANLILGMLQADPSKRLSLQEIRHDTWFRSA 438
            ||..:.|..|.:.|.....   |||.    :.....::|||||:.||..||.|.|::..||
 Worm   354 PFVDNYIIALHKKIKNDPIVFPEAPI----LSEALQDIILGMLKKDPGHRLMLHEVKVHTW---- 410

  Fly   439 PVKTGPPIP---------IPPLKGDKYRNST-VIPYLEAY----------HYGTQEEDVYFTEHD 483
             |.....:|         :..:..::..|.. |||.|:..          .:|..
 Worm   411 -VTRDGTVPMSSEQENCHLVTVTEEEIENCVRVIPRLDTLILVKAMGHRKRFGNP---------- 464

  Fly   484 VNQELARQAAAAASEIRAKQSAAALAACHTYEPPSTSAAAASNSLGNGSREEAPVKK------KG 542
                 .|...:|.|.||.::.::::.. .||.||..|..|.||:..|.::.:.|..|      .|
 Worm   465 -----FRNKLSAQSSIRDRRKSSSVKD-PTYVPPPNSPPATSNNNLNSTKVDRPEIKCIEMNLSG 523

  Fly   543 SALK 546
            ..||
 Worm   524 LTLK 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lkb1	NP_001163606.1	S_TKc	172..435	CDD:214567	106/291 (36%)
		STKc_LKB1	178..435	CDD:271021	105/285 (37%)
ckk-1	NP_001021153.1	S_TKc	130..411	CDD:214567	107/296 (36%)
		STKc_CAMKK	135..412	CDD:271020	106/292 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910