Protein Alignment Lkb1 and sad-1

DIOPT Version :9

• Sequence 1: NP_001163606.1
• Gene: Lkb1 / 41673
• FlyBaseID: FBgn0038167
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: NP_001076760.1
• Gene: sad-1 / 181471
• WormBaseID: WBGene00004719
• Length: 914
• Species: Caenorhabditis elegans
• Alignment Length: 422
• Identity: 126/422 - (29%)
• Similarity: 206/422 - (48%)
• Gaps: 58/422 - (13%)

  Fly   144 MGNMFFNRVDSQDIIYQQKKKSIKMVGKYIMGDVLGEGSYGKVKEAMNSENLCRLAVKILTKRKL 208
            :.|...:::.|::|:..:.....:..|.|.:...||:|..|.||...:.....::|:||:.|.||
 Worm    19 VNNELSSKIMSENIVSTRPVAQAQYCGPYKLEKTLGKGQTGLVKTGTHCITGRKVAIKIVNKEKL 83

  Fly   209 RRIPNGEQNVTREIALLKQLKHRHVVELVDVLYNEEKQKMYLVMEYCVGGLQEMIDYQPDK-RMP 272
            ..  :..|.|.||||::|.::|.||:.|.||.  |.|:.:||::|:..||  |:.||...| |:.
 Worm    84 SE--SVLQKVEREIAIMKLIEHPHVLHLYDVY--ENKKYLYLLLEHVSGG--ELFDYLVRKGRLM 142

  Fly   273 LFQAHGYFKQLVDGLEYLHSCRVIHKDIKPGNLLLSLDQTLKISDFGVAE-QLDLFAPDDTCTTG 336
            ..:|..:|:|::..|::.|:..:.|:|:||.||||.....:|::|||:|. |::....:.:|
 Worm   143 SKEARKFFRQIISALDFCHAHNICHRDLKPENLLLDERNNIKVADFGMASLQVEGSMLETSC--- 204

  Fly   337 QGSPAFQPPEIANGHETFAGFKVDIWSSGVTLYNLATGQYPFEGDNIYRLLENIGRGQWEAPAWL 401
             |||.:..||:..| |.:.|.|.|:||.||.||.|..|..||:.||:..|||.:.||.:..|
 Worm   205 -GSPHYACPEVIRG-EKYDGRKADVWSCGVILYALLVGALPFDDDNLRNLLEKVKRGVFHIP--- 264

  Fly   402 YEMDADFANLILGMLQADPSKRLSLQEIRHDTWFRSAPVKTGPPIPIP--------PLKGD---- 454
            :.:.||..:|:..|::.||.||.||.::....|. |...|..|.:.:|        .:.|:
 Worm   265 HFVPADVQSLLRAMIEVDPGKRYSLADVFKHPWV-SGTTKADPELELPMSQVVQTHVIPGEDSID 328

  Fly   455 -------------KYRNSTVIPYLEAYHYGTQEEDVYFTEHDVNQELARQAAAAASEIRAKQSAA 506
                         |.:...:...|...|  ..|:.|||...|  ::..|.|....:||..:
 Worm   329 PDVLRHMNCLGCFKDKQKLINELLSPKH--NTEKMVYFLLLD--RKRRRPAQEDDTEIVLR---- 385

  Fly   507 ALAACHTYEPPS--TSAAAAS----NSLGNGS 532
              .|....:||.  |.::..|    .|:.:||
 Worm   386 --GAAQNNDPPKKRTDSSRTSRYPMGSIADGS 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lkb1	NP_001163606.1	S_TKc	172..435	CDD:214567	96/264 (36%)
		STKc_LKB1	178..435	CDD:271021	95/258 (37%)
sad-1	NP_001076760.1	STKc_BRSK1_2	45..298	CDD:270983	97/266 (36%)
		S_TKc	47..298	CDD:214567	96/264 (36%)
		UBA_BRSK	327..379	CDD:270525	10/55 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910