Protein Alignment Lkb1 and mark4

DIOPT Version :9

• Sequence 1: NP_001163606.1
• Gene: Lkb1 / 41673
• FlyBaseID: FBgn0038167
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: XP_012824414.1
• Gene: mark4 / 100491038
• XenbaseID: XB-GENE-6042140
• Length: 681
• Species: Xenopus tropicalis
• Alignment Length: 396
• Identity: 116/396 - (29%)
• Similarity: 196/396 - (49%)
• Gaps: 46/396 - (11%)

  Fly   169 VGKYIMGDVLGEGSYGKVKEAMNSENLCRLAVKILTKRKLRRIPNGEQNVTREIALLKQLKHRHV 233
            ||.|.:...:|:|::.|||.|.:......:|:||:.|.:|.  |:..|.:.||:.::|.|.|.::
 Frog    48 VGNYRLLRTIGKGNFAKVKLARHVLTGREVAIKIIDKTQLN--PSSLQKLFREVRIMKGLNHPNI 110

  Fly   234 VELVDVLYNEEKQKMYLVMEYCVGGLQEMIDYQPDK-RMPLFQAHGYFKQLVDGLEYLHSCRVIH 297
            |:|.:|:  |.::.:||:|||..||  |:.||.... ||...:|...|:|:|..:.|.|...::|
 Frog   111 VKLFEVI--ETEKTLYLIMEYASGG--EVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVH 171

  Fly   298 KDIKPGNLLLSLDQTLKISDFGVAEQLDLFAPDDTCTTGQGSPAFQPPEIANGHETFAGFKVDIW 362
            :|:|..||||..:..:||:|||.:.:   |.|.....|..|||.:..||:..| :.:.|.:||:|
 Frog   172 RDLKAENLLLDSESNIKIADFGFSNE---FTPGGKLDTFCGSPPYAAPELFQG-KRYNGPEVDVW 232

  Fly   363 SSGVTLYNLATGQYPFEGDNIYRLLENIGRGQWEAPAWLYEMDADFANLILGMLQADPSKRLSLQ 427
            |.||.||.|.:|..||:|.|:..|.|.:.||::..|   :.|..|...::...|..:||||.:|.
 Frog   233 SLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIP---FYMSTDCEGVLRRFLVLNPSKRCTLD 294

  Fly   428 EIRHDTW----FRSAPVKTGPPIPIPPLKGDKYRNSTV--IPYLEAYHYGTQEEDVYFTEHDVNQ 486
            :|.:|.|    |.|..:|        |.|..:..|:..  |..:....|..:|.....:.:..|:
 Frog   295 QIMNDKWMNIGFDSDDLK--------PYKEPEEDNADPKRIEIMLEMGYSREEIKDALSSNKYNE 351

  Fly   487 ELA------RQAAAAASEIRAKQSAAALAACHTYEPPSTSAAAASNSLGNGSREEAPVKKKGSAL 545
            .:|      |:..:...|.|:..:.            |.|.:..::.:.||:.:.:.|..|....
 Frog   352 VMATYLLLGRKPESEGGESRSDSTL------------SLSRSRVASDVTNGATKSSSVHSKNQRG 404

  Fly   546 KRRAKK 551
            .:|.::
 Frog   405 YQRQRR 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lkb1	NP_001163606.1	S_TKc	172..435	CDD:214567	93/267 (35%)
		STKc_LKB1	178..435	CDD:271021	92/261 (35%)
mark4	XP_012824414.1	STKc_MARK	50..302	CDD:270974	92/264 (35%)
		UBA_MARK_Par1	323..361	CDD:270522	5/37 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910