Protein Alignment Lkb1 and brsk2b

DIOPT Version :9

• Sequence 1: NP_001163606.1
• Gene: Lkb1 / 41673
• FlyBaseID: FBgn0038167
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: XP_009301700.1
• Gene: brsk2b / 100149571
• ZFINID: ZDB-GENE-100422-3
• Length: 886
• Species: Danio rerio
• Alignment Length: 333
• Identity: 114/333 - (34%)
• Similarity: 176/333 - (52%)
• Gaps: 35/333 - (10%)

  Fly   169 VGKYIMGDVLGEGSYGKVKEAMNSENLCRLAVKILTKRKLRRIPNGEQNVTREIALLKQLKHRHV 233
            ||.|.:...||:|..|.||..::.....::|:||:.:.||..  :....|.||||:||.::|.||
Zfish    17 VGPYRLEKTLGKGQTGLVKLGIHCVTCQKVAIKIVNREKLSE--SVLMKVEREIAILKLIEHPHV 79

  Fly   234 VELVDVLYNEEKQKMYLVMEYCVGGLQEMIDYQPDK-RMPLFQAHGYFKQLVDGLEYLHSCRVIH 297
            ::|.||.  |.|:.:|||:|:..||  |:.||...| |:...:|..:|:|::..|::.||..:.|
Zfish    80 LKLHDVY--ENKKYLYLVLEHVSGG--ELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICH 140

  Fly   298 KDIKPGNLLLSLDQTLKISDFGVAEQLDLFAPDDTCTTGQGSPAFQPPEIANGHETFAGFKVDIW 362
            :|:||.||||.....::|:|||:|   .|...|....|..|||.:..||:..| |.:.|.|.|:|
Zfish   141 RDLKPENLLLDEKNNIRIADFGMA---SLQVGDSLLETSCGSPHYACPEVIRG-EKYDGRKADVW 201

  Fly   363 SSGVTLYNLATGQYPFEGDNIYRLLENIGRGQWEAPAWLYEMDADFANLILGMLQADPSKRLSLQ 427
            |.||.|:.|..|..||:.||:..|||.:..|.:..|.::   ..|..||:.||::.|.:|||:|:
Zfish   202 SCGVILFALLVGALPFDDDNLRNLLEKVKLGVFHMPHFI---PPDCQNLLRGMIEVDATKRLTLE 263

  Fly   428 EIRHDTWFRSAPVKTGPPIPIPPLKGDKYRNST--VIP-YLEAYHY------------------G 471
            :|:..||:.....:..|..|:|.....:...||  :.| .||:.|.                  .
Zfish   264 QIQKHTWYIGGKNEPEPEQPVPRKVAIRTLPSTEDIDPDVLESMHSLGCFRDKNKLMKDLLSDDD 328

  Fly   472 TQEEDVYF 479
            .||:.:||
Zfish   329 NQEKMIYF 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lkb1	NP_001163606.1	S_TKc	172..435	CDD:214567	98/263 (37%)
		STKc_LKB1	178..435	CDD:271021	97/257 (38%)
brsk2b	XP_009301700.1	STKc_BRSK1_2	18..271	CDD:270983	99/265 (37%)
		S_TKc	20..270	CDD:214567	97/262 (37%)
		UBA_BRSK	298..351	CDD:270525	8/39 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910