DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9588 and NMA111

DIOPT Version :9

Sequence 1:	NP_650301.1	Gene:	CG9588 / 41672	FlyBaseID:	FBgn0038166	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	NP_014276.1	Gene:	NMA111 / 855600	SGDID:	S000005067	Length:	997	Species:	Saccharomyces cerevisiae

Alignment Length:	224	Identity:	47/224 - (20%)
Similarity:	79/224 - (35%)	Gaps:	73/224 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 GTTTKERLERLINAKKQLEAQINRNGQI-----------LAANDNVGMSG-PLVDAEGF------ 50
            |....|:|..|.....:::......|::           .||:.:.|.|| |:|:.:|:
Yeast   188 GNDAGEKLSILAGFISRIDRNAPEYGELTYNDFNTEYIQAAASASGGSSGSPVVNIDGYAVALQA 252

  Fly    51 -----PRNDIDVYQVRLARQTIICLQNDHKELMN---QIQTLLNQYHSEIATTDPELVNRASALD 107
                 ...|..:...|:.| .:||:|. :|.:..   |:|.||..|            :....|.
Yeast   253 GGSTEASTDFFLPLDRILR-ALICIQT-NKPITRGTIQVQWLLKPY------------DECRRLG 303

  Fly   108 LDSDRSPGGANITDLAPARAIVVVNLVSPDSPAERAGLCAGDAILRFG-------------SINS 159
            |.|:|.         :.|||....|:          ||...:.:||.|             |||
Yeast   304 LTSERE---------SEARAKFPENI----------GLLVAETVLREGPGYDKIKEGDTLISIN- 348

  Fly   160 GNFKGDLAQIGELVRNMQSQNVQLKVKRG 188
            |.......|:.::......:.:||.::||
Yeast   349 GETISSFMQVDKIQDENVGKEIQLVIQRG 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9588	NP_650301.1	PDZ	116..186	CDD:238080	16/82 (20%)
NMA111	NP_014276.1	DegQ	48..391	CDD:223343	47/224 (21%)
		PDZ_1	392..469	CDD:372324
		DegQ	543..870	CDD:223343
		PDZ	<810..862	CDD:412172
		PDZ	869..944	CDD:412172
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0265
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900