DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9588 and htra3b

DIOPT Version :9

Sequence 1:	NP_650301.1	Gene:	CG9588 / 41672	FlyBaseID:	FBgn0038166	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	XP_021333811.1	Gene:	htra3b / 573378	ZFINID:	ZDB-GENE-110602-1	Length:	466	Species:	Danio rerio

Alignment Length:	213	Identity:	43/213 - (20%)
Similarity:	78/213 - (36%)	Gaps:	78/213 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 RNGQILAAND------------NVGMS-GPLVDAEGFPRNDIDVYQVRLARQTIICLQND----- 73
            |:|:.|...|            |.|.| ||||:.:|   ..|.:..:::|......:.:|
Zfish   288 RDGKELGLQDSDMDYIQTDAIINYGNSGGPLVNLDG---EVIGINTLKVAAGISFAIPSDRITRF 349

  Fly    74 --------HKELMN--------QIQTLLNQYHSEIATTDPELVNRASALDLDSDRSPGGANITDL 122
                    :||..:        ::.|:.:....|:...:|:.          .|.|.|
Zfish   350 LNDSLGKQNKETRSVKKRFIGIRMLTITDALVEELKQQNPDF----------PDVSSG------- 397

  Fly   123 APARAIVVVNLVSPDSPAERAGLCAGDAILRFGS---INSGNFKGDLAQIGELVRNMQSQNVQLK 184
                  :.|:.|.|.|||::.|:..||.|::...   :::.:.|..|         .|...:.|:
Zfish   398 ------IFVHEVVPHSPAQKGGIRDGDIIVKLNGEPLLSTSDLKEAL---------NQDMTLLLE 447

  Fly   185 VKRGEQQL------DLIL 196
            |:||...|      |:|:
Zfish   448 VRRGNDDLLFNIEPDIIM 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9588	NP_650301.1	PDZ	116..186	CDD:238080	14/72 (19%)
htra3b	XP_021333811.1	IGFBP	24..75	CDD:306685
		KAZAL	87..133	CDD:197624
		DegQ	152..>438	CDD:333159	34/175 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0265
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900