DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9588 and htra4

DIOPT Version :9

Sequence 1:	NP_650301.1	Gene:	CG9588 / 41672	FlyBaseID:	FBgn0038166	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	XP_017211746.2	Gene:	htra4 / 100334257	ZFINID:	ZDB-GENE-131120-192	Length:	459	Species:	Danio rerio

Alignment Length:	188	Identity:	47/188 - (25%)
Similarity:	70/188 - (37%)	Gaps:	62/188 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 NVGMS-GPLVDAEGFPRNDIDVYQVRLARQT-----------IICLQNDHKELMNQIQTLLNQYH 89
            |.|.| ||||:.:|      ||..:...:.|           |.....|..|...:.:||..:.:
Zfish   304 NYGNSGGPLVNLDG------DVIGINTLKVTPGISFAIPSDRIRQFLADSYERQRKGRTLTKKKY 362

  Fly    90 SEI------ATTDPELVNRASALDLDSDRSPGGANITDLAPARAIVVVNLVSPDSPAERAGLCAG 148
            ..:      |....||..:.|:.   .|.|.|             |.|..|.|.:.|..||:...
Zfish   363 MGVRMLQLSAALIRELREKESSF---PDVSSG-------------VYVYEVIPGTAAFSAGMLNQ 411

  Fly   149 DAILRFGSINSGNFKGDLAQIGELVRNMQ--SQNVQ------LKVKRGEQQLDLILVP 198
            |.|:   |||           |:.|.:.:  ||.||      |.|:|.::::.|.:||
Zfish   412 DVII---SIN-----------GQPVYSTEDVSQAVQSNEILSLMVRRAQKEITLTVVP 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9588	NP_650301.1	PDZ	116..186	CDD:238080	19/77 (25%)
htra4	XP_017211746.2	IGFBP	27..80	CDD:306685
		KAZAL_FS	92..135	CDD:238052
		DegQ	118..459	CDD:223343	47/188 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0265
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900