DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Task6 and kcnk9

DIOPT Version :9

Sequence 1:	NP_001262541.1	Gene:	Task6 / 41671	FlyBaseID:	FBgn0038165	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_001122021.1	Gene:	kcnk9 / 799704	ZFINID:	ZDB-GENE-070705-260	Length:	399	Species:	Danio rerio

Alignment Length:	353	Identity:	160/353 - (45%)
Similarity:	219/353 - (62%)	Gaps:	49/353 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKKQNVRTISLIVCTFTYLLVGAAVFDALESETEKRRWEALQDAEDMIIRKYNISQEDFKVMETV 65
            ||:|||||:||||||||||||||||||||||:.|.|..|.|:..|..:..|||||::|:|.::|:
Zfish     1 MKRQNVRTLSLIVCTFTYLLVGAAVFDALESDFEMREKEQLEAEEKRLQGKYNISEDDYKKLQTI 65

  Fly    66 VLKSESHKAGQQWKFTGAFYYATTVLTTIGYGHSTPSTVGGKLFTMCYAIVGIPLGLVMFQSIGE 130
            ::::|.|:||.||||.|:||:|.||:|||||||:.|.|..||.|.|.||::||||.||||||:||
Zfish    66 IMEAEPHRAGVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLVMFQSLGE 130

  Fly   131 RVNRLSSYVIKAVRSSLRCKRTVASEVDLICVVTTLSSLTIAGGAAAFSKFEGWSYFDSVYYCFI 195
            |:|....|::|.::.....:.|..|..:::.|.......|:..||||||::|.||:|.|.|||||
Zfish   131 RMNTFVKYLLKRIKKCCGMRITEVSMENMVTVGFFSCMGTLCIGAAAFSQYEDWSFFQSYYYCFI 195

  Fly   196 TLTTIGFGDMVALQRDNALNRKPEYVMFALIFILFGLAIVAASLNLLVLRFVTMNTEDERRDEAQ 260
            |||||||||.||||::.||.:||.||.|:.::||.||.::.|.|||:||||:|||:||||||
Zfish   196 TLTTIGFGDFVALQKNKALQKKPLYVAFSFMYILVGLTVIGAFLNLVVLRFLTMNSEDERRD--- 257

  Fly   261 AMQALQVAVKLEGDVITSNGSILSGYEGHDGQSLNGSNTSSMCSCHCICLNGNRHKKSSNLEKNN 325
                                       ..:..||.|:.:|.:.......|..:|.::...
Zfish   258 ---------------------------AEERASLAGNRSSMIIHIQEDTLQRSRRRREQQ----- 290

  Fly   326 DAENQYKLRQSPTHIRHLLPEVVPMQDL 353
              :|:|:            |||..:|.:
Zfish   291 --QNRYR------------PEVTDLQSV 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Task6	NP_001262541.1	Ion_trans_2	<77..132	CDD:285168	37/54 (69%)
Task6	NP_001262541.1	Ion_trans_2	169..247	CDD:285168	48/77 (62%)
kcnk9	NP_001122021.1	Ion_trans_2	<77..132	CDD:285168	37/54 (69%)
kcnk9	NP_001122021.1	Ion_trans_2	170..243	CDD:285168	45/72 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590203
Domainoid	1	1.000	114	1.000	Domainoid score	I6016
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	317	1.000	Inparanoid score	I2520
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1109218at2759
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	1	1.000	-	-		mtm6514
orthoMCL	1	0.900	-	-		OOG6_103570
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	10.900