Protein Alignment Task6 and Kcnk16

DIOPT Version :10

• Sequence 1: NP_650300.2
• Gene: Task6 / 41671
• FlyBaseID: FBgn0038165
• Length: 408
• Species: Drosophila melanogaster
• Sequence 2: NP_083282.1
• Gene: Kcnk16 / 74571
• MGIID: 1921821
• Length: 292
• Species: Mus musculus
• Alignment Length: 245
• Identity: 79/245 - (32%)
• Similarity: 126/245 - (51%)
• Gaps: 14/245 - (5%)

  Fly     7 RTISLIVCTFTYLLVGAAVFDALESETEKRRWEALQDAEDMIIRKYN-ISQEDFKVMETVVL--- 67
            :.:.|::....|||:||.:|..||.:.|.:..:..|..:...:..|. :.|:..:....|:|
Mouse    13 QVLPLLLAYICYLLLGATIFQLLEKQAEAQSRDQFQLEKLRFLENYTCLDQQALEQFVQVILEAW 77

  Fly    68 -KSESHKAG----QQWKFTGAFYYATTVLTTIGYGHSTPSTVGGKLFTMCYAIVGIPLGLVMFQS 127
             |..:.|..    ..|.|..:|::|.||:||||||:..|||..|::|.:.||::||||.:|....
Mouse    78 VKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALMGIPLNVVFLNH 142

  Fly   128 IGERVNRLSSYVIKAVRSSLRCKRTVASEVDLICVVTTLSSLTI-AGGAAAFSKFEGWSYFDSVY 191
            :|   ..|.:::....|.....:.:...:|..:.:..||.:|.| ......||..||||:.:..|
Mouse   143 LG---TGLRAHLTTLDRWEDHPRHSQLLQVLGLALFLTLGTLVILIFPPMFFSHVEGWSFREGFY 204

  Fly   192 YCFITLTTIGFGDMVALQRDNALNRKPEYVMFALIFILFGLAIVAASLNL 241
            :.||||:||||||.| :..|.:.:....|...|.|:||.|||.:|..|:|
Mouse   205 FAFITLSTIGFGDYV-VGTDPSKHYIAVYRSLAAIWILLGLAWLAVVLSL 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Task6	NP_650300.2	Ion_trans_2	<78..132	CDD:462301	25/53 (47%)
		Ion_trans_2	165..243	CDD:462301	34/78 (44%)
Kcnk16	NP_083282.1	Ion_trans_2	87..145	CDD:462301	25/60 (42%)
		Selectivity filter 1. /evidence=ECO:0000250|UniProtKB:Q96T55	108..113		4/4 (100%)
		Ion_trans_2	180..248	CDD:462301	29/68 (43%)
		Selectivity filter 2. /evidence=ECO:0000250|UniProtKB:Q96T55	212..217		4/4 (100%)