Protein Alignment Task6 and Kcnk13

DIOPT Version :10

• Sequence 1: NP_650300.2
• Gene: Task6 / 41671
• FlyBaseID: FBgn0038165
• Length: 408
• Species: Drosophila melanogaster
• Sequence 2: NP_071629.2
• Gene: Kcnk13 / 64120
• RGDID: 68941
• Length: 405
• Species: Rattus norvegicus
• Alignment Length: 434
• Identity: 121/434 - (27%)
• Similarity: 199/434 - (45%)
• Gaps: 86/434 - (19%)

  Fly     1 MKKQNVRTISLIVCTFTYLLVGAAVFDALESETE---KRRWEALQDAEDMIIRKYNISQEDFKVM 62
            :.:.|.|.:.|......|||.|||||.|||...|   |:|||   :......|.:|:|:|:.:..
  Rat    13 LNEDNARFLLLAGLILLYLLGGAAVFSALELAQELQAKQRWE---ERLANFSRGHNLSREELRGF 74

  Fly    63 ETVVLK--SESHKAG-------QQWKFTGAFYYATTVLTTIGYGHSTPSTVGGKLFTMCYAIVGI 118
                |:  .|:.|||       .:|.||||||:..||:||||:|.:||:|.|||:|.:.|.::|.
  Rat    75 ----LRHYEEATKAGIRMDSVRPRWDFTGAFYFVGTVVTTIGFGMTTPATTGGKVFLIFYGLIGC 135

  Fly   119 PLGLVMFQSIGERVNRLSSYVIKAV-RSSLRCKRTVASE-------------------VDLICVV 163
            ...::.|....||:..:.:||::.. ...||.:.|||.:                   |..:.::
  Rat   136 ASTILFFNLFLERLITVIAYVMRTCHHQQLRRRGTVARDNGKAPRKGEADSLAGWKPSVYYVMLI 200

  Fly   164 TTLSSLTIAGGAAA-FSKFEGWSYFDSVYYCFITLTTIGFGDMVALQRDNALNRKPEYVMFALIF 227
            ..|:|:.|:.||:| ::..||||||||||:||:..:||||||:|:.|.....| :..|......|
  Rat   201 LCLASVAISCGASALYTTMEGWSYFDSVYFCFVAFSTIGFGDLVSSQNAQYEN-EGLYRFVNFFF 264

  Fly   228 ILFGLAIVAASLNLL-VLRFVTMNTEDERRDEAQAMQALQVAVKLEGDVITSNGSILSGYEGHDG 291
            ||.|:..:.:..|:: :|...|:|....:.|.....|..:..::...:|:
  Rat   265 ILMGVCCIYSMFNVISILIKQTVNWILRKLDSGCFPQCQRGLLRSRRNVV--------------- 314

  Fly   292 QSLNGSNTSSMCSCHCICLNGN-RHKKSSNLEKNNDAENQYKLRQSPTHIRHLLPEVVPMQDLN- 354
                              :.|| |::.:.::|.:.       :.:|.|..|.|..|::.|:|.|
  Rat   315 ------------------MPGNIRNRCNISIETDG-------VMESDTDGRRLSGEMISMKDTNK 354

  Fly   355 --YDYDTQSLHTLADRGTMDSSYMGVDMADMGDTGSMELRPHTL 396
              .....:.|..:|:.|...:|....|....|..|:..:..:.|
  Rat   355 VSLAILQKQLSEMANGGPHQTSTSSRDDEFSGGVGAFAVMNNRL 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Task6	NP_650300.2	Ion_trans_2	<78..132	CDD:462301	25/53 (47%)
		Ion_trans_2	165..243	CDD:462301	33/79 (42%)
Kcnk13	NP_071629.2	Ion_trans_2	84..150	CDD:462301	28/65 (43%)
		Selectivity filter 1. /evidence=ECO:0000250|UniProtKB:P57789	110..115		3/4 (75%)
		Ion_trans_2	203..285	CDD:462301	34/82 (41%)
		Selectivity filter 2. /evidence=ECO:0000250|UniProtKB:P57789	237..242		4/4 (100%)