Protein Alignment Task6 and KCNK12

DIOPT Version :9

• Sequence 1: NP_001262541.1
• Gene: Task6 / 41671
• FlyBaseID: FBgn0038165
• Length: 408
• Species: Drosophila melanogaster
• Sequence 2: NP_071338.1
• Gene: KCNK12 / 56660
• HGNCID: 6274
• Length: 430
• Species: Homo sapiens
• Alignment Length: 404
• Identity: 98/404 - (24%)
• Similarity: 163/404 - (40%)
• Gaps: 124/404 - (30%)

  Fly     7 RTISLIVCTFTYLLVGAAVFDALES--ETEKR-RWEALQDAEDMIIRKYN----ISQEDFKVM-- 62
            |.:.|......||:.||.||.||||  |.|.| ||.|       .:|.::    :::.:.:..
Human    38 RFVLLAALIGLYLVAGATVFSALESPGEAEARARWGA-------TLRNFSAAHGVAEPELRAFLR 95

  Fly    63 ---ETVVLKSESHKAGQQWKFTGAFYYATTVLTTIGYGHSTPSTVGGKLFTMCYAIVGIPLGLVM 124
               ..:.....:.....:|.|.||||:..||::|||:|.:||:|||||.|.:.|.:.|....::.
Human    96 HYEAALAAGVRADALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGCAGTILF 160

  Fly   125 FQSIGERVNRLSSYVIKAVRS-SLR---------CKRTVASEVD-----------LICVVTTLSS 168
            |....||:..|.:::::|.|. .||         .:.:..||.|           ::.::...:.
Human   161 FNLFLERIISLLAFIMRACRERQLRRSGLLPATFRRGSALSEADSLAGWKPSVYHVLLILGLFAV 225

  Fly   169 LTIAGGAAAFSKFEGWSYFDSVYYCFITLTTIGFGDMVALQ----RDNALNRKPEYVMFALIFIL 229
            |.....:|.::..|||.|.||:|:||:|.:||||||:|:.|    |:..|.|...:     :|||
Human   226 LLSCCASAMYTSVEGWDYVDSLYFCFVTFSTIGFGDLVSSQHAAYRNQGLYRLGNF-----LFIL 285

  Fly   230 FGLAIVAASLNLLVLRFVTMNTEDERRDEAQAMQALQVAVKLEGDVITSNGSILSGYEGHDGQSL 294
            .|:..:.:..|:                       :.:.:|                     |.|
Human   286 LGVCCIYSLFNV-----------------------ISILIK---------------------QVL 306

  Fly   295 NGSNTSSMCSCHCIC--------------LNGNRHKK------SSNLEKNNDAENQYKLRQSPTH 339
            |.......|.|...|              ..|:|.::      :....:::|||.
Human   307 NWMLRKLSCRCCARCCPAPGAPLARRNAITPGSRLRRRLAALGADPAARDSDAEG---------- 361

  Fly   340 IRHLLPEVVPMQDL 353
             |.|..|::.|:||
Human   362 -RRLSGELISMRDL 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Task6	NP_001262541.1	Ion_trans_2	<77..132	CDD:285168	24/54 (44%)
		Ion_trans_2	169..247	CDD:285168	28/81 (35%)
KCNK12	NP_071338.1	Ion_trans_2	101..169	CDD:400301	25/67 (37%)
		Ion_trans_2	222..304	CDD:400301	29/130 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155127
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4404
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740