Protein Alignment Task6 and KCNK10

DIOPT Version :9

• Sequence 1: NP_001262541.1
• Gene: Task6 / 41671
• FlyBaseID: FBgn0038165
• Length: 408
• Species: Drosophila melanogaster
• Sequence 2: NP_612190.1
• Gene: KCNK10 / 54207
• HGNCID: 6273
• Length: 543
• Species: Homo sapiens
• Alignment Length: 280
• Identity: 92/280 - (32%)
• Similarity: 145/280 - (51%)
• Gaps: 40/280 - (14%)

  Fly     1 MKKQNVRTISLIVCTFTYLLVGAAVFDALES--ETEKRRWEALQDAEDMIIRKY-NISQEDFKVM 62
            ||.:.|  :::.|....||:.|..||.|||.  |:.::...||:.||  .:|.: .:|.::   :
Human    72 MKWKTV--VAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAE--FLRDHVCVSPQE---L 129

  Fly    63 ETVVLKS-ESHKAG-----------QQWKFTGAFYYATTVLTTIGYGHSTPSTVGGKLFTMCYAI 115
            ||::..: ::..||           ..|....||::|.||:||||||:..|||.|||:|.:.|||
Human   130 ETLIQHALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAI 194

  Fly   116 VGIPLGLVMFQSIGERVNRLSSYVIKAVRSSLRCKRTVASEVDLICVVTTLSSLTIAGG------ 174
            .||||...:...||:::..:....|..|....|.|:...:::.:|..:     |.|..|
Human   195 FGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTI-----LFILAGCIVFVT 254

  Fly   175 --AAAFSKFEGWSYFDSVYYCFITLTTIGFGDMVALQRDNA-LNRKPEYVMFALIFILFGLAIVA 236
              |..|...|||:..:|:|:..:||||:||||.||  ..|| :|.:..|......:||.|||..|
Human   255 IPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVA--GGNAGINYREWYKPLVWFWILVGLAYFA 317

  Fly   237 ASLNLL--VLRFVTMNTEDE 254
            |.|:::  .||.::..|::|
Human   318 AVLSMIGDWLRVLSKKTKEE 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Task6	NP_001262541.1	Ion_trans_2	<77..132	CDD:285168	28/54 (52%)
		Ion_trans_2	169..247	CDD:285168	34/88 (39%)
KCNK10	NP_612190.1	Ion_trans_2	153..211	CDD:285168	28/57 (49%)
		Ion_trans_2	249..328	CDD:285168	29/80 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155117
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2827
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.870