DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Task6 and kcnk1

DIOPT Version :9

Sequence 1:	NP_001262541.1	Gene:	Task6 / 41671	FlyBaseID:	FBgn0038165	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_001011490.1	Gene:	kcnk1 / 496985	XenbaseID:	XB-GENE-5846322	Length:	330	Species:	Xenopus tropicalis

Alignment Length:	250	Identity:	79/250 - (31%)
Similarity:	129/250 - (51%)	Gaps:	28/250 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 ISLIVCTFTYLLVGAAVFDALESETEKRRWEALQDAEDMIIRKYN-ISQEDFKVMETVVLKSESH 72
            :.|::....:||:|||:|.|:|...|....|.|.|.:...:::.. :|:|..:...:.||::.::
Frog    24 VLLMLGYLLFLLIGAAIFSAVELPHEHVLREELLDLKHRYLQENECLSEERLESFLSRVLEASNY 88

  Fly    73 --------KAGQQWKFTGAFYYATTVLTTIGYGHSTPSTVGGKLFTMCYAIVGIPLGLVMFQSIG 129
                    .....|.||.|.::.:|||:|.||||:.|.:..||.|.:.|:|:||||.|::|.::.
Frog    89 GVSMLNNVSGNPNWDFTSALFFVSTVLSTTGYGHTVPLSNAGKTFCIIYSIIGIPLTLLLFTALV 153

  Fly   130 ERV-----NRLSSYVIKAVRSSLRC---KRTVASEVDLIC-VVTTLSSLTIAGGAAAFSKFE-GW 184
            :|:     :|..||.      .||.   |:|||....|:. .|..|....|.  ||.||..| .|
Frog   154 QRIMVHVTHRPISYF------HLRWGYNKQTVAVVHALVIGFVAILCFFLIP--AAIFSALEDDW 210

  Fly   185 SYFDSVYYCFITLTTIGFGDMVALQRDNALNRKPEYVMFALIFILFGLAIVAASL 239
            ::.:|.|:|||:|:|||.||.|..:..|...|: .|......:::.||.::...|
Frog   211 NFLESFYFCFISLSTIGLGDYVPAEGQNQRYRQ-LYKFGITCYLILGLIVMLVVL 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Task6	NP_001262541.1	Ion_trans_2	<77..132	CDD:285168	24/54 (44%)
Task6	NP_001262541.1	Ion_trans_2	169..247	CDD:285168	24/71 (34%)
kcnk1	NP_001011490.1	Ion_trans_2	<101..157	CDD:311712	25/55 (45%)
kcnk1	NP_001011490.1	Ion_trans_2	192..267	CDD:311712	25/75 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910