Protein Alignment Task6 and Kcnk18

DIOPT Version :9

• Sequence 1: NP_001262541.1
• Gene: Task6 / 41671
• FlyBaseID: FBgn0038165
• Length: 408
• Species: Drosophila melanogaster
• Sequence 2: NP_997144.1
• Gene: Kcnk18 / 332396
• MGIID: 2685627
• Length: 394
• Species: Mus musculus
• Alignment Length: 358
• Identity: 84/358 - (23%)
• Similarity: 125/358 - (34%)
• Gaps: 136/358 - (37%)

  Fly     9 ISLIVCTFTYLLVGAAVFDALESETEKRRWEALQDAEDMIIRKY-----NISQEDFKVME----- 63
            :..:.|..||.|||||:|.|:|...:.   ||.::.|   ::|:     ||.:.:..|:|
Mouse    35 LCFLCCLVTYALVGAALFSAVEGRPDP---EAEENPE---LKKFLDDLCNILKCNLTVVEGSRKN 93

  Fly    64 ----TVVLKSESHKAGQQWKFTGAFYYATTVLTTIGYGHSTPSTVGGKLFTMCYAIVGIPLGLVM 124
                ...||.:..||.|.|.|..|.::..||.:|:||||..|.|..||...|.||:.||||..::
Mouse    94 LCEHLQHLKPQWLKAPQDWSFLSALFFCCTVFSTVGYGHMYPVTRLGKFLCMLYALFGIPLMFLV 158

  Fly   125 FQSIG------------------------------------------------------------ 129
            ...||
Mouse   159 LTDIGDILATILSRAYSRFQALLCLPHDIFKWRSLPLCRKQPDSKPVEEAIPQIVIDAGVDELLN 223

  Fly   130 -----------------------ERVNRLSSYVIKAVRSSLRCKRTV------------------ 153
                                   |:.|:|.. ..:.|..|..|...|
Mouse   224 PQPSKDPPSPSCNVELFERLVAREKKNKLQP-PTRPVERSNSCPELVLGRLSCSILSNLDEVGQQ 287

  Fly   154 ASEVDLICVVTTLSSLTIAGGAAAFSKFEGW----SYFDSVYYCFITLTTIGFGDMVALQRDNAL 214
            ...:|:...|..|........|||...|  |    .:.|:.|:||:|||||||||:|.:.
Mouse   288 VERLDIPLPVIALVVFAYISCAAAILPF--WETELGFEDAFYFCFVTLTTIGFGDIVLVH----- 345

  Fly   215 NRKPEYVMFALIFILFGLAIVAASLNLLVLRFV 247
               |.:.:|..|:|:.|:.|:..:..|:..|.:
Mouse   346 ---PHFFLFFSIYIIVGMEILFIAFKLMQNRLL 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Task6	NP_001262541.1	Ion_trans_2	<77..132	CDD:285168	24/137 (18%)
		Ion_trans_2	169..247	CDD:285168	27/81 (33%)
Kcnk18	NP_997144.1	Ion_trans_2	<111..166	CDD:285168	23/54 (43%)
		Interaction with calcineurin	210..215		0/4 (0%)
		Interaction with YWHAH. /evidence=ECO:0000269|PubMed:18397886	261..266		1/4 (25%)
		Ion_trans_2	300..376	CDD:285168	28/86 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845603
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840