DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Task6 and Kcnk15

DIOPT Version :9

Sequence 1:	NP_001262541.1	Gene:	Task6 / 41671	FlyBaseID:	FBgn0038165	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_001025463.1	Gene:	Kcnk15 / 241769	MGIID:	2675209	Length:	343	Species:	Mus musculus

Alignment Length:	255	Identity:	132/255 - (51%)
Similarity:	178/255 - (69%)	Gaps:	0/255 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKKQNVRTISLIVCTFTYLLVGAAVFDALESETEKRRWEALQDAEDMIIRKYNISQEDFKVMETV 65
            |:||:.||.:||:|..:|||||||||||||||.|:.|...|........|||..|.:|::.:|.:
Mouse    20 MRKQSARTAALILCILSYLLVGAAVFDALESEAERSRQRLLARKRGEFRRKYRFSADDYRELERL 84

  Fly    66 VLKSESHKAGQQWKFTGAFYYATTVLTTIGYGHSTPSTVGGKLFTMCYAIVGIPLGLVMFQSIGE 130
            .|::|.|:||:||:|.|:||:|.||:|||||||:.|.|..||:|.|.||::||||.||.|||:||
Mouse    85 ALQAEPHRAGRQWRFAGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPLTLVTFQSLGE 149

  Fly   131 RVNRLSSYVIKAVRSSLRCKRTVASEVDLICVVTTLSSLTIAGGAAAFSKFEGWSYFDSVYYCFI 195
            |:|.|...::...:..|..:|...|..:::.....|.:.|:|.||.||:.||||::|.:.|||||
Mouse   150 RLNTLVRCLLLTAKRCLGLRRPHVSAENMVVAGLLLCAATLALGAIAFAHFEGWTFFHAYYYCFI 214

  Fly   196 TLTTIGFGDMVALQRDNALNRKPEYVMFALIFILFGLAIVAASLNLLVLRFVTMNTEDER 255
            |||||||||.||||||.||.|||.||.|:.::||.||.::.|.|||:||||:..:...||
Mouse   215 TLTTIGFGDFVALQRDEALQRKPPYVAFSFLYILLGLTVIGAFLNLVVLRFLASSDAPER 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Task6	NP_001262541.1	Ion_trans_2	<77..132	CDD:285168	35/54 (65%)
Task6	NP_001262541.1	Ion_trans_2	169..247	CDD:285168	50/77 (65%)
Kcnk15	NP_001025463.1	Ion_trans_2	<96..151	CDD:285168	35/54 (65%)
Kcnk15	NP_001025463.1	Ion_trans_2	195..262	CDD:285168	43/66 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845574
Domainoid	1	1.000	111	1.000	Domainoid score	I6230
eggNOG	1	0.900	-	-		E1_KOG4404
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	297	1.000	Inparanoid score	I2701
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49311
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	1	1.000	-	-		mtm8804
orthoMCL	1	0.900	-	-		OOG6_103570
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2827
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.790