DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Task6 and Kcnk9

DIOPT Version :9

Sequence 1:	NP_001262541.1	Gene:	Task6 / 41671	FlyBaseID:	FBgn0038165	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	XP_006520831.1	Gene:	Kcnk9 / 223604	MGIID:	3521816	Length:	604	Species:	Mus musculus

Alignment Length:	286	Identity:	154/286 - (53%)
Similarity:	199/286 - (69%)	Gaps:	21/286 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKKQNVRTISLIVCTFTYLLVGAAVFDALESETEKRRWEALQDAEDMIIR-KYNISQEDFKVMET 64
            ||:|||||:|||.||||||||||||||||||:.|.|..|.|: ||::.:| |||||.:|::.:|.
Mouse   203 MKRQNVRTLSLIACTFTYLLVGAAVFDALESDHEMREEEKLK-AEEVRLRGKYNISSDDYQQLEL 266

  Fly    65 VVLKSESHKAGQQWKFTGAFYYATTVLTTIGYGHSTPSTVGGKLFTMCYAIVGIPLGLVMFQSIG 129
            |:|:||.|:||.||||.|:||:|.||:|||||||:.|.|..||.|.|.||::||||.||||||:|
Mouse   267 VILQSEPHRAGVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLVMFQSLG 331

  Fly   130 ERVNRLSSYVIKAVRSSLRCKRTVASEVDLICVVTTLSSLTIAGGAAAFSKFEGWSYFDSVYYCF 194
            ||:|....|::|.::.....:.|..|..:::.|.......|:..||||||:.|.||:|.:.||||
Mouse   332 ERMNTFVRYLLKRIKKCCGMRNTEVSMENMVTVGFFSCMGTLCLGAAAFSQCEDWSFFHAYYYCF 396

  Fly   195 ITLTTIGFGDMVALQRDNALNRKPEYVMFALIFILFGLAIVAASLNLLVLRFVTMNTEDERRDEA 259
            ||||||||||.||||...||.|||.||.|:.::||.||.::.|.|||:||||:||||::|
Mouse   397 ITLTTIGFGDFVALQAKGALQRKPFYVAFSFMYILVGLTVIGAFLNLVVLRFLTMNTDEE----- 456

  Fly   260 QAMQALQVAVKLEGDVITSNGSILSG 285
                      .|||:|    ..||:|
Mouse   457 ----------LLEGEV----AEILAG 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Task6	NP_001262541.1	Ion_trans_2	<77..132	CDD:285168	37/54 (69%)
Task6	NP_001262541.1	Ion_trans_2	169..247	CDD:285168	48/77 (62%)
Kcnk9	XP_006520831.1	Ion_trans_2	<279..334	CDD:400301	37/54 (69%)
Kcnk9	XP_006520831.1	Ion_trans_2	372..445	CDD:400301	45/72 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845587
Domainoid	1	1.000	111	1.000	Domainoid score	I6230
eggNOG	1	0.900	-	-		E1_KOG4404
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	297	1.000	Inparanoid score	I2701
Isobase	1	0.950	-	0	Normalized mean entropy	S2198
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1109218at2759
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	1	1.000	-	-		mtm8804
orthoMCL	1	0.900	-	-		OOG6_103570
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2827
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.740