DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Task6 and twk-32

DIOPT Version :9

Sequence 1:	NP_001262541.1	Gene:	Task6 / 41671	FlyBaseID:	FBgn0038165	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_506416.2	Gene:	twk-32 / 192075	WormBaseID:	WBGene00006684	Length:	614	Species:	Caenorhabditis elegans

Alignment Length:	380	Identity:	84/380 - (22%)
Similarity:	139/380 - (36%)	Gaps:	129/380 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 ISLIVCTFTYLLVG----------------AAVFDALESETEKR--------RWEALQDAEDMII 49
            |:|:|.:..|.:.|                |.:||.......||        .:|::.|  :::.
Worm    37 ITLLVVSILYAVFGGWMLTLIKYSQQTTHQAIMFDQTRQNFAKRLALIGNKEEFESIVD--ELVE 99

  Fly    50 RKYNISQEDFKVMETVVLKSESHKAGQQWK-----------FTGAFYYATTVLTTIGYGHSTPST 103
            :.|     ||..||.          |.:|:           ||...::|.|.||:||||...|.:
Worm   100 KTY-----DFYTMED----------GHRWQEAAFNANPLTNFTSNLFFAATTLTSIGYGIDAPES 149

  Fly   104 VGGKLFTMCYAIVGIPLGLV----MFQSIGERVNRLSSYVIK-AVRSSLRCKRTVASEVDLICVV 163
            :.|::|.:.|...||||.|:    |.:...|.:||..:.:|| ..|...|.||..:..:....:
Worm   150 LIGRVFCLVYLFFGIPLYLITIADMAKFCTELMNRTYTEIIKYKYRVKRRYKRWKSGRIRRESM- 213

  Fly   164 TTLSSLTIAGGAAAFSKF------------------------------------EGWSYFDSVYY 192
             .:..:.||||....::|                                    |.|:..|..|:
Worm   214 -KVGQVIIAGGEDEVAEFLWTHLEHAQFVEVPFLLVIGILLLYIGLSSWIISWVENWNMMDGFYF 277

  Fly   193 CFITLTTIGFGDMVALQRDNALNRKPEYVMFA---LIFILFGLAIVAASLNLL------VLRFVT 248
            ..:::.||||||:|           |...:||   |..||.||.:....::::      .|.|..
Worm   278 VMMSVLTIGFGDLV-----------PRNEIFAVPILFIILAGLVLTTTCIDVVGAYYIDRLHFFG 331

  Fly   249 MNTED----------ERRDEAQAMQAL----QVAVKLEGDVITSNGSILSGYEGH 289
            ...:|          :||.||...:|:    :....|....:|:...:...|:.|
Worm   332 RRLDDDPLSWLKEVQQRRIEAMKKEAMRKLFETVTALHHIRLTAFKQLTQNYDEH 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Task6	NP_001262541.1	Ion_trans_2	<77..132	CDD:285168	22/69 (32%)
Task6	NP_001262541.1	Ion_trans_2	169..247	CDD:285168	25/122 (20%)
twk-32	NP_506416.2	Ion_trans_2	<125..180	CDD:285168	20/54 (37%)
		Ion_trans_2	251..325	CDD:285168	19/84 (23%)
		FN3	392..485	CDD:238020
		FN3	491..580	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910