Protein Alignment Task6 and twk-22

DIOPT Version :10

• Sequence 1: NP_650300.2
• Gene: Task6 / 41671
• FlyBaseID: FBgn0038165
• Length: 408
• Species: Drosophila melanogaster
• Sequence 2: NP_001361830.1
• Gene: twk-22 / 181703
• WormBaseID: WBGene00006675
• Length: 749
• Species: Caenorhabditis elegans
• Alignment Length: 476
• Identity: 102/476 - (21%)
• Similarity: 191/476 - (40%)
• Gaps: 127/476 - (26%)

  Fly     2 KKQNVRTISLIVCTFTYLLVGAAVF-------DALESETEK--RRWEALQDAEDMI--IRKYNIS 55
            |...::.:.|.:....|..:|..:|       ..|:.|.||  |..|:...||:::  ::::|..
 Worm   170 KLLGIQYMLLALMILGYACLGGYIFLTLEYDQQQLDLEVEKQVRLSESTLLAENLLKYLKQWNCG 234

  Fly    56 QEDFK----------VMETVVLKSESHKAGQQWKFTGAFYYATTVLTTIGYGHSTPSTVGGKLFT 110
            |.:..          :..::.::.:....|.:|.|..:.:::.|:.||||||:....|..|::.|
 Worm   235 QSNENRCLELITKAFIERSIKVERDIRGEGWRWDFWNSVFFSATIFTTIGYGNLACKTNLGRVAT 299

  Fly   111 MCYAIVGIPLGLVMFQSIGERVNRLSSYVIKAVRSSL-RCKR-----------TVASEVDLICVV 163
            :.|.::||||.|.:.:..||...:.:..|..::|..: ||.|           :|||: ::.|..
 Worm   300 IIYGLIGIPLMLFVLKIFGEHSIKWAQKVRYSIRRCVKRCFRRSKLKRASTIESVASD-EMPCEE 363

  Fly   164 TTLSS-----LTIAGGAAAF-------------SKFEGWSYFDSVYYCFITLTTIGFGDMVALQR 210
            :.:|.     .|.....|.|             |.:|.|.:..:.|:.|::|:||||||::
 Worm   364 SGISEDEEQITTFPVKWALFIVFFFMVVCSLIVSFWEKWDFLTAFYFFFVSLSTIGFGDVI---- 424

  Fly   211 DNALNRKPEY-----VMFALIFILFGLAIVAASLNLLVLRFVTMNTEDERRDEAQAMQALQVA-- 268
                   ||:     .:|.|.|:  |||:.:....:|           :.|.|.|.|.||::.
 Worm   425 -------PEHPRTACALFVLYFV--GLALFSMVYAIL-----------QERVENQYMWALELIDQ 469

  Fly   269 -----VKLEGD-------VITSNGSILSGYEGHDGQSLNGSNTSSMCSCHCICLNGNRHKKSS-- 319
                 .|.:.|       ::..|.:.:.|:....|:.::.:....            |.|.|:
 Worm   470 EYQENQKQDPDDHLEIPTILPENAAGMEGWTNTIGKMVSQNPVRW------------RAKNSAYS 522

  Fly   320 --NLEKNNDAENQYKLRQSPTHIRHLLPEVVPMQDLNYDYDTQSLHTLADRGTMDSSYMGVDMAD 382
              |:.....:|.::.: .||.......|.|:         .|..||:|    ::....:....:.
 Worm   523 MENMPDRPISERRFSV-LSPGEAPQAPPPVL---------GTFMLHSL----SVKKKLLARSESI 573

  Fly   383 MGDTGSMELRPHTLLKRNVSL 403
            :..||:.  ||.||...|..|
 Worm   574 LNRTGTK--RPSTLFPSNEML 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Task6	NP_650300.2	Ion_trans_2	<78..132	CDD:462301	20/53 (38%)
		Ion_trans_2	165..243	CDD:462301	24/100 (24%)
twk-22	NP_001361830.1	Ion_trans_2	<262..319	CDD:462301	19/56 (34%)
		Ion_trans_2	380..458	CDD:462301	24/101 (24%)