DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Task6 and sup-9

DIOPT Version :9

Sequence 1:	NP_001262541.1	Gene:	Task6 / 41671	FlyBaseID:	FBgn0038165	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_494333.1	Gene:	sup-9 / 173613	WormBaseID:	WBGene00006318	Length:	329	Species:	Caenorhabditis elegans

Alignment Length:	321	Identity:	170/321 - (52%)
Similarity:	227/321 - (70%)	Gaps:	16/321 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKKQNVRTISLIVCTFTYLLVGAAVFDALESETEKRRWEALQDAEDMIIRKYNISQEDFKVMETV 65
            ||:||:||:||||||.||||||||||||||:|.|..:.:.:|...:.:..|||:|..|::::|..
Worm     1 MKRQNIRTLSLIVCTLTYLLVGAAVFDALETENEILQRKLVQRVREKLKTKYNMSNADYEILEAT 65

  Fly    66 VLKSESHKAGQQWKFTGAFYYATTVLTTIGYGHSTPSTVGGKLFTMCYAIVGIPLGLVMFQSIGE 130
            ::||..||||.||||:||||:||||:||||||||||.|..||:|.|.||:.||||||:|||||||
Worm    66 IVKSVPHKAGYQWKFSGAFYFATTVITTIGYGHSTPMTDAGKVFCMLYALAGIPLGLIMFQSIGE 130

  Fly   131 RVNRLSSYVIKAVRSSLRCKRTVASEVDLICVVTTLSSLTIAGGAAAFSKFEGWSYFDSVYYCFI 195
            |:|..::.:::.:|.:.. |:.:.:..|||...|....|.|.|||..||.:|.|:|||:|||||:
Worm   131 RMNTFAAKLLRFIRRAAG-KQPIVTSSDLIIFCTGWGGLLIFGGAFMFSSYENWTYFDAVYYCFV 194

  Fly   196 TLTTIGFGDMVALQRDNALNRKPEYVMFALIFILFGLAIVAASLNLLVLRFVTMNTEDERRDEAQ 260
            |||||||||.||||:..:|..:||||.|:|:||||||.:::|::|||||||:|||||||||||.:
Worm   195 TLTTIGFGDYVALQKRGSLQTQPEYVFFSLVFILFGLTVISAAMNLLVLRFLTMNTEDERRDEQE 259

  Fly   261 AMQALQVAVKLEGDVITSNGSILSGYEGHDGQSLNGSNTSSMCSCHCICLNG----NRHKK 317
            |:.|.|..|:: ||....:          |...|..|:..|:.||.|..|..    :||:|
Worm   260 AILAAQGLVRV-GDPTADD----------DFGRLPLSDNVSLASCSCYQLPDEKLRHRHRK 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Task6	NP_001262541.1	Ion_trans_2	<77..132	CDD:285168	42/54 (78%)
Task6	NP_001262541.1	Ion_trans_2	169..247	CDD:285168	50/77 (65%)
sup-9	NP_494333.1	Ion_trans_2	<77..132	CDD:311712	42/54 (78%)
sup-9	NP_494333.1	Ion_trans_2	168..242	CDD:311712	46/73 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163766
Domainoid	1	1.000	114	1.000	Domainoid score	I3801
eggNOG	1	0.900	-	-		E1_KOG4404
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H136701
Inparanoid	1	1.050	330	1.000	Inparanoid score	I1438
Isobase	1	0.950	-	0	Normalized mean entropy	S2198
OMA	1	1.010	-	-		QHG49311
OrthoDB	1	1.010	-	-		D1109218at2759
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	1	1.000	-	-		otm14802
orthoMCL	1	0.900	-	-		OOG6_103570
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2827
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	17	16.750