DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Task6 and Kcnk15

DIOPT Version :9

Sequence 1:	NP_001262541.1	Gene:	Task6 / 41671	FlyBaseID:	FBgn0038165	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_570826.1	Gene:	Kcnk15 / 156873	RGDID:	619733	Length:	318	Species:	Rattus norvegicus

Alignment Length:	255	Identity:	133/255 - (52%)
Similarity:	179/255 - (70%)	Gaps:	0/255 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKKQNVRTISLIVCTFTYLLVGAAVFDALESETEKRRWEALQDAEDMIIRKYNISQEDFKVMETV 65
            |:||:.||.:||:|..:|||||||||||||||.|:.|...|........|||..|.:|::.:|.:
  Rat     1 MRKQSARTAALILCILSYLLVGAAVFDALESEAERSRQRLLARKRGEFRRKYRFSADDYRELERL 65

  Fly    66 VLKSESHKAGQQWKFTGAFYYATTVLTTIGYGHSTPSTVGGKLFTMCYAIVGIPLGLVMFQSIGE 130
            .|::|.|:||:||:|.|:||:|.||:|||||||:.|.|..||:|.|.||::||||.||.|||:||
  Rat    66 ALQAEPHRAGRQWRFAGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPLTLVTFQSLGE 130

  Fly   131 RVNRLSSYVIKAVRSSLRCKRTVASEVDLICVVTTLSSLTIAGGAAAFSKFEGWSYFDSVYYCFI 195
            |:|.|...::.|.:..|..:|...|..:::.....|.:.|:|.|||||:.||||::|.:.|||||
  Rat   131 RLNALVRCLLLAAKRCLGLRRPHVSAENMVVAGLLLCAATLALGAAAFAHFEGWTFFHAYYYCFI 195

  Fly   196 TLTTIGFGDMVALQRDNALNRKPEYVMFALIFILFGLAIVAASLNLLVLRFVTMNTEDER 255
            |||||||||.||||||.||.:||.||.|:.::||.||.::.|.|||:||||:......||
  Rat   196 TLTTIGFGDFVALQRDEALQKKPPYVAFSFLYILLGLTVIGAFLNLVVLRFLASAEAPER 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Task6	NP_001262541.1	Ion_trans_2	<77..132	CDD:285168	35/54 (65%)
Task6	NP_001262541.1	Ion_trans_2	169..247	CDD:285168	50/77 (65%)
Kcnk15	NP_570826.1	Ion_trans_2	<77..132	CDD:285168	35/54 (65%)
		Ion_trans_2	<182..243	CDD:285168	39/60 (65%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	296..318
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348986
Domainoid	1	1.000	112	1.000	Domainoid score	I6047
eggNOG	1	0.900	-	-		E1_KOG4404
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	296	1.000	Inparanoid score	I2654
OMA	1	1.010	-	-		QHG49311
OrthoDB	1	1.010	-	-		D1109218at2759
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	1	1.000	-	-		mtm9050
orthoMCL	1	0.900	-	-		OOG6_103570
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.770