DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Task6 and kcnk15

DIOPT Version :9

Sequence 1:	NP_001262541.1	Gene:	Task6 / 41671	FlyBaseID:	FBgn0038165	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	XP_004918713.1	Gene:	kcnk15 / 100492337	XenbaseID:	XB-GENE-6065312	Length:	411	Species:	Xenopus tropicalis

Alignment Length:	387	Identity:	175/387 - (45%)
Similarity:	239/387 - (61%)	Gaps:	32/387 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKKQNVRTISLIVCTFTYLLVGAAVFDALESETEKRRWEALQDAEDMIIRKYNISQEDFKVMETV 65
            |||||:||:|||:|.|:|||||||||||||||:|..|...|::....:..||..|.||::.:|.|
Frog    13 MKKQNIRTLSLILCMFSYLLVGAAVFDALESESEISRKRILEEKRLNLRNKYGFSDEDYREIERV 77

  Fly    66 VLKSESHKAGQQWKFTGAFYYATTVLTTIGYGHSTPSTVGGKLFTMCYAIVGIPLGLVMFQSIGE 130
            |.:||.|:||:||||.|:||:|.||:|||||||:.|.|..||:|.|.||::||||.||||||:||
Frog    78 VQQSEPHRAGKQWKFAGSFYFAITVITTIGYGHAAPGTDAGKVFCMFYAVLGIPLTLVMFQSLGE 142

  Fly   131 RVNRLSSYVIKAVRSSLRCKRTVASEVDLICVVTTLSSL-TIAGGAAAFSKFEGWSYFDSVYYCF 194
            |:|....:::|.::...|.::|..|..::: :|..||.: |:..||||||.||||::|.|.||||
Frog   143 RMNTFVRFLLKKLKRCFRLRKTEVSMENMV-LVGFLSCIGTLGIGAAAFSYFEGWTFFHSYYYCF 206

  Fly   195 ITLTTIGFGDMVALQRDNALNRKPEYVMFALIFILFGLAIVAASLNLLVLRFVTMNTEDERRD-- 257
            ||||||||||.||||::.||.:||.||.|:.::||.||.::.|.|||:||||:|||:||||||
Frog   207 ITLTTIGFGDFVALQKNEALQKKPPYVAFSFMYILVGLTVIGAFLNLVVLRFLTMNSEDERRDAE 271

  Fly   258 EAQAMQALQVAVKLEGDVIT-SNGSILSG--------------YEGHDGQSLNGSNTSSMCSCHC 307
            |..:::..|..:.|:..:|: |..||...              .|..|......|||.|.....|
Frog   272 ERASLRRAQNNINLQSSLISRSRSSIFLPLGDRTSQINLIPLMQEDSDRDRPRASNTPSRAGSFC 336

  Fly   308 ICLNGNRHKKSSNLEKNNDAENQYKLRQSPTHIRHLLPEVVPMQDLNYDYDTQSLHTLADRG 369
            .|:....|...|....:::           |.|.|..|  |....:::..|..||.|..:.|
Frog   337 TCMCYRSHFCDSPAISHHE-----------TLICHTNP--VYYNSISFKIDEISLSTRDNTG 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Task6	NP_001262541.1	Ion_trans_2	<77..132	CDD:285168	37/54 (69%)
Task6	NP_001262541.1	Ion_trans_2	169..247	CDD:285168	49/78 (63%)
kcnk15	XP_004918713.1	Ion_trans_2	<89..144	CDD:369572	37/54 (69%)
kcnk15	XP_004918713.1	Ion_trans_2	<192..255	CDD:369572	39/62 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	111	1.000	Domainoid score	I6158
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H136701
Inparanoid	1	1.050	327	1.000	Inparanoid score	I2421
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1109218at2759
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	1	1.000	-	-		mtm9469
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060