Protein Alignment B52 and SRSF9

DIOPT Version :9

• Sequence 1: NP_001014619.2
• Gene: B52 / 41670
• FlyBaseID: FBgn0004587
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: NP_003760.1
• Gene: SRSF9 / 8683
• HGNCID: 10791
• Length: 221
• Species: Homo sapiens
• Alignment Length: 251
• Identity: 96/251 - (38%)
• Similarity: 124/251 - (49%)
• Gaps: 65/251 - (25%)

  Fly     5 RVYVGGLPYGVRERDLERFFKGYGRTRDILIKNGYG-----FVEFEDYRDADDAVYELNGKELLG 64
            |:|||.||..|||:|||..|..|||.|:|.:||.:|     ||.|||.|||:||:|..||.:...
Human    15 RIYVGNLPTDVREKDLEDLFYKYGRIREIELKNRHGLVPFAFVRFEDPRDAEDAIYGRNGYDYGQ 79

  Fly    65 ERVVVEPARGTARGSNRDRYDDRYGGRRGGGGGRYNEKNKNSRSSSRYGPPL-RTEYRLIVENLS 128
            .|:.||             :...||||.|...|            .|.|||. |:::|::|..|.
Human    80 CRLRVE-------------FPRTYGGRGGWPRG------------GRNGPPTRRSDFRVLVSGLP 119

  Fly   129 SRVSWQDLKDYMRQAGEVTYADAHKQRRNEGVVEFASLSDMKTAIEKLDDTELNGR-------RI 186
            ...|||||||:||:||:|.|||.  |:...|:||:....||:.|:.|||||:....       |:
Human   120 PSGSWQDLKDHMREAGDVCYADV--QKDGVGMVEYLRKEDMEYALRKLDDTKFRSHEGETSYIRV 182

  Fly   187 HLVEDRRGGRSGGGGGSGRGRSRSSS---SRSRSRSRRRS---RSRRSSHSRSKSR 236
            :                   ..||:|   |||||.||.|.   :||.|.|..|..|
Human   183 Y-------------------PERSTSYGYSRSRSGSRGRDSPYQSRGSPHYFSPFR 219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B52	NP_001014619.2	RRM1_SRSF4_like	5..74	CDD:240783	37/73 (51%)
		RRM2_SRSF4_like	120..191	CDD:241044	31/77 (40%)
SRSF9	NP_003760.1	RRM1_SRSF9	15..86	CDD:241042	37/83 (45%)
		RRM2_SRSF9	104..186	CDD:410161	34/102 (33%)
		Interaction with SAFB1	188..200		6/11 (55%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	189..221		15/31 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1315388at2759
OrthoFinder	1	1.000	-	-		FOG0000217
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1390
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.850