Protein Alignment B52 and Srsf6

DIOPT Version :9

• Sequence 1: NP_001014619.2
• Gene: B52 / 41670
• FlyBaseID: FBgn0004587
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: NP_080775.3
• Gene: Srsf6 / 67996
• MGIID: 1915246
• Length: 339
• Species: Mus musculus
• Alignment Length: 351
• Identity: 210/351 - (59%)
• Similarity: 244/351 - (69%)
• Gaps: 37/351 - (10%)

  Fly     5 RVYVGGLPYGVRERDLERFFKGYGRTRDILIKNGYGFVEFEDYRDADDAVYELNGKELLGERVVV 69
            |||:|.|.|.|||:|::|||.||||..:|.:|||||||||||.|||||||||||.|||.||||:|
Mouse     3 RVYIGRLSYNVREKDIQRFFSGYGRLLEIDLKNGYGFVEFEDSRDADDAVYELNSKELCGERVIV 67

  Fly    70 EPARGTARGSNRDRYDDRYGGRRGGGGGRYNEKNKNSRSSSRYGPPLRTEYRLIVENLSSRVSWQ 134
            |.|||..|  :||.|.  ||.|.||||  |:.:..:.|  .:||||:||||||||||||||.|||
Mouse    68 EHARGPRR--DRDGYS--YGSRSGGGG--YSSRRTSGR--DKYGPPVRTEYRLIVENLSSRCSWQ 124

  Fly   135 DLKDYMRQAGEVTYADAHKQRRNEGVVEFASLSDMKTAIEKLDDTELNGRRIHLVEDRRGGRSGG 199
            ||||:||||||||||||||:|.||||:||.|.||||.|::|||.||:|||.|.|:||:  .|:.
Mouse   125 DLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDK--PRTS- 186

  Fly   200 GGGSGRGRSRSSSSRSRSRSRRRSRSRRSSHSRSKSRSRSKSRGGRSKSKSPVKSRSRSRSRSNK 264
                  .|...|.||||||||||||||....|||:|||.|||   ||:|:|..|.||||||:..|
Mouse   187 ------HRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKS---RSRSRSRSKGRSRSRSKGRK 242

  Fly   265 SRDVSKSKSK----SHSRTRSRSPKRERDSRSRSRSVSKRE-------SRSRSRSKSIHRD---- 314
            ||..||||.|    |||.:||||..:...|||||||.|.:|       |:|||||:|....
Mouse   243 SRSKSKSKPKSDRGSHSHSRSRSKDKYGKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSHSPLPA 307

  Fly   315 --SRSRDRSASAENKSRSRSRSRSAS 338
              |::|..|...:..|||||||||.|
Mouse   308 PPSKARSMSPPPKRASRSRSRSRSRS 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B52	NP_001014619.2	RRM1_SRSF4_like	5..74	CDD:240783	50/68 (74%)
		RRM2_SRSF4_like	120..191	CDD:241044	55/70 (79%)
Srsf6	NP_080775.3	RRM_SF	1..72	CDD:418427	50/68 (74%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	75..103		13/35 (37%)
		RRM2_SRSF6	110..182	CDD:410159	56/71 (79%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	176..339		85/170 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	113	1.000	Domainoid score	I6120
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	350	1.000	Inparanoid score	I2265
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000217
OrthoInspector	1	1.000	-	-		otm44168
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23147
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1390
SonicParanoid	1	1.000	-	-		X517
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.950