DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment B52 and Nono

DIOPT Version :9

Sequence 1:	NP_001014619.2	Gene:	B52 / 41670	FlyBaseID:	FBgn0004587	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	XP_030107241.1	Gene:	Nono / 53610	MGIID:	1855692	Length:	482	Species:	Mus musculus

Alignment Length:	181	Identity:	40/181 - (22%)
Similarity:	71/181 - (39%)	Gaps:	50/181 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SRVYVGGLPYGVRERDLERFFKGYGRTRDILI--KNGYGFVEFEDYRDADDAVYELNGKELLGER 66
            ||::||.||..:.|.::.:.|:.||:..::.|  ..|:||:..|....|:.|..||:...|.|::
Mouse    76 SRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAKVELDNMPLRGKQ 140

  Fly    67 VVVEPARGTARGSNRDRYDDRYGGRRGGGGGRYNEKNKNSRSSSRYGPPLRTEYRLIVENLSSRV 131
            :.|..|..:|                                            .|.|.||...|
Mouse   141 LRVRFACHSA--------------------------------------------SLTVRNLPQYV 161

  Fly   132 SWQDLKDYMRQAGEVTYA----DAHKQRRNEGVVEFASLSDMKTAIEKLDD 178
            |.:.|::.....|:|..|    |...:...:|:|||:.....:.|:::..:
Mouse   162 SNELLEEAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKALDRCSE 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
B52	NP_001014619.2	RRM1_SRSF4_like	5..74	CDD:240783	22/70 (31%)
B52	NP_001014619.2	RRM2_SRSF4_like	120..191	CDD:241044	16/63 (25%)
Nono	XP_030107241.1	RRM1_p54nrb	75..145	CDD:241032	22/68 (32%)
		RRM_SF	151..230	CDD:388407	16/62 (26%)
		NOPS_p54nrb_PSF_PSPC1	221..313	CDD:240581
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910