DRSC/TRiP Functional Genomics Resources

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Protein Alignment B52 and MYEF2

DIOPT Version :10

Sequence 1:NP_788671.2 Gene:B52 / 41670 FlyBaseID:FBgn0004587 Length:355 Species:Drosophila melanogaster
Sequence 2:NP_057216.3 Gene:MYEF2 / 50804 HGNCID:17940 Length:600 Species:Homo sapiens


Alignment Length:150 Identity:47/150 - (31%)
Similarity:72/150 - (48%) Gaps:24/150 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    75 TARGSNRDRYDDRYGGRRGGGGGRYNEKNKNSRSSSRYGPPLRTEYRLIVENLSSRVSWQDLKDY 139
            :|:....|..:...|.::......|: |:|||.:..:.||   ...|:.:.|:...:.||.:||.
Human    59 SAKEEKSDLKEKSTGSKKANRFHPYS-KDKNSGAGEKKGP---NRNRVFISNIPYDMKWQAIKDL 119

  Fly   140 MRQ-AGEVTYA----DAHKQRRNEGVVEFASLSDMKTAIEKLDDTELNGRRIHLVED-------- 191
            ||: .|||||.    ||..:.|..|||||.....:|.|:|.::..:|:||.:::.||        
Human   120 MREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETMNKYDLSGRPLNIKEDPDGENARR 184

  Fly   192 ---RRGGRSGGGG----GSG 204
               |.||...||.    |||
Human   185 ALQRTGGSFPGGHVPDMGSG 204

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
B52NP_788671.2 RRM1_SRSF4_like 5..74 CDD:409774
RRM2_SRSF4_like 120..191 CDD:410012 27/75 (36%)
MYEF2NP_057216.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..101 10/45 (22%)
RRM1_MYEF2 101..176 CDD:410059 27/74 (36%)
PABP-1234 124..>596 CDD:130689 28/80 (35%)
RRM2_MYEF2 233..308 CDD:410061
RRM3_MYEF2 524..600 CDD:410063
Blue background indicates that the domain is not in the aligned region.

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