Protein Alignment B52 and Srsf2

DIOPT Version :10

• Sequence 1: NP_788671.2
• Gene: B52 / 41670
• FlyBaseID: FBgn0004587
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: NP_001009720.1
• Gene: Srsf2 / 494445
• RGDID: 1359422
• Length: 221
• Species: Rattus norvegicus
• Alignment Length: 314
• Identity: 108/314 - (34%)
• Similarity: 126/314 - (40%)
• Gaps: 134/314 - (42%)

  Fly     8 VGGLPYGVRERDLERFFKGYGRTRDILI--------KNGYGFVEFEDYRDADDAVYELNGKELLG 64
            |..|.|......|.|.|:.|||..|:.|        ..|:.||.|.|.|||:||:..::|..|.|
  Rat    18 VDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMDAMDGAVLDG 82

  Fly    65 ERVVVEPARGTARGSNRDRYDDRYGGRRGGGGGRYNEKNKNSRSSSRYGPPLRTEYRLIVENLSS 129
            ..:.|:.|                                      |||.|
  Rat    83 RELRVQMA--------------------------------------RYGRP-------------- 95

  Fly   130 RVSWQDLKDYMRQAGEVTYADAHKQRRNEGVVEFASLSDMKTAIEKLDDTELNGRRIHLVEDRRG 194
                               .|:|..||..                                   .
  Rat    96 -------------------PDSHHSRRGP-----------------------------------P 106

  Fly   195 GRSGGGGGSGRGRSRSSSSRSRSRSRRRSRSRRSSHSRSKSRSRSKSRGGRSKSKSPVKSRSRSR 259
            .|..||||.|| ||||      .|.|||||||    |||:|||||:||..||||:|..:|||||.
  Rat   107 PRRYGGGGYGR-RSRS------PRRRRRSRSR----SRSRSRSRSRSRYSRSKSRSRTRSRSRST 160

  Fly   260 SRSNKSRDVSKSKSKSHSRTRSRSPKRERDSRSRSRS---VSKRESRSRSRSKS 310
            |:|..:|. |||||.|.||:||||     .|||||||   ||||||:|||||||
  Rat   161 SKSRSARR-SKSKSSSVSRSRSRS-----RSRSRSRSPPPVSKRESKSRSRSKS 208

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B52	NP_788671.2	RRM1_SRSF4_like	5..74	CDD:409774	26/73 (36%)
		RRM2_SRSF4_like	120..191	CDD:410012	4/70 (6%)
Srsf2	NP_001009720.1	RRM_SRSF2_SRSF8	16..88	CDD:409751	24/69 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	92..221		81/202 (40%)