Protein Alignment B52 and srsf7a

DIOPT Version :10

• Sequence 1: NP_788671.2
• Gene: B52 / 41670
• FlyBaseID: FBgn0004587
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: NP_991236.1
• Gene: srsf7a / 402972
• ZFINID: ZDB-GENE-040426-1798
• Length: 258
• Species: Danio rerio
• Alignment Length: 358
• Identity: 126/358 - (35%)
• Similarity: 154/358 - (43%)
• Gaps: 131/358 - (36%)

  Fly     5 RVYVGGLPYGVRERDLERFFKGYGRTRDILIKN---GYGFVEFEDYRDADDAVYELNGKELLGER 66
            :||||.|..|..:.:|||.|..||..|.:.:..   |:.|||:||.|||:|||..::||.|.|.|
Zfish    15 KVYVGDLGNGAAKGELERAFSYYGPLRSVWVARNPPGFAFVEYEDARDAEDAVKGMDGKVLCGAR 79

  Fly    67 VVVEPARGTARGSNRDRYDDRYGGRRGGGGGRYNEKNKNSRSSSRYGPPLRTEYRLIVENLSSRV 131
            |.||.:.|.:|                               .||||.|.|.::
Zfish    80 VRVELSNGMSR-------------------------------KSRYGRPSRRQF----------- 102

  Fly   132 SWQDLKDYMRQAGEV-TYA-DAHKQRRNEGVVEFASLSDMKTAIEKLDDTELNGRRIHLVEDRRG 194
               |..|...|.||. .|| |.::                                   ...||.
Zfish   103 ---DPNDRCYQCGETGHYAYDCYR-----------------------------------FSKRRS 129

  Fly   195 GRSGGGGGSGRGRSRSSSSRSRSRSRRR-----SRSRRSSHSRSKSRSRSKSRGGRS-----KSK 249
            .||..|..| |.|||....||||||..|     |.|:|.|.|.|..||||:|.||||     :||
Zfish   130 RRSRSGSRS-RSRSRGRRYRSRSRSNERRYRSPSYSKRRSRSGSPGRSRSRSPGGRSRSPVRRSK 193

  Fly   250 SPVKSRSRSRSRSNKSRDVSKSKSKSHSRTRSRSPKRERDSRSRSRSVSKRESRSRSRSKSIHRD 314
            |||:   |||||:...||       |.||:||||..|:||     |||    |||||||:||
Zfish   194 SPVR---RSRSRTPLHRD-------SRSRSRSRSGSRQRD-----RSV----SRSRSRSRSI--- 236

  Fly   315 SRSRDRSASAENKSRSRSRSRSASPKNGNASPD 347
            |..:|            |.||||||:. :.:||
Zfish   237 SHKKD------------SHSRSASPRR-SPTPD 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B52	NP_788671.2	RRM1_SRSF4_like	5..74	CDD:409774	33/71 (46%)
		RRM2_SRSF4_like	120..191	CDD:410012	8/72 (11%)
srsf7a	NP_991236.1	RRM_SF	15..91	CDD:473069	35/106 (33%)
		zf-CCHC	106..121	CDD:395050	6/14 (43%)