DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment B52 and tia1

DIOPT Version :9

Sequence 1:	NP_001014619.2	Gene:	B52 / 41670	FlyBaseID:	FBgn0004587	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	XP_012814227.2	Gene:	tia1 / 394890	XenbaseID:	XB-GENE-1002876	Length:	389	Species:	Xenopus tropicalis

Alignment Length:	194	Identity:	48/194 - (24%)
Similarity:	83/194 - (42%)	Gaps:	38/194 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VYVGGLPYGVRERDLERFFKGYGRTR------DILIKNGYGFVEFEDYRDADDAVYELNGKELLG 64
            :|||.|...|.|..:.:.|...|..:      |....:.|.||||.::|.|..::..:||::::|
Frog     9 LYVGNLSRDVTEPLILQVFSQLGPCKSCKMIMDTAGNDPYCFVEFFEHRHAAASLAAMNGRKIMG 73

  Fly    65 ERVVVEPARGTARGSNRDRYDDRYGGRRGGGGGRYNEKNKNSRSSSRYGPPLRTE--YRLIVENL 127
            :.|.|..|  |...|.:                      |::.|||... .||::  :.:.|.:|
Frog    74 KEVKVNWA--TTPSSQK----------------------KDANSSSVVS-TLRSQDHFHVFVGDL 113

  Fly   128 SSRVSWQDLKDYMRQAGEVTYADAHK-----QRRNEGVVEFASLSDMKTAIEKLDDTELNGRRI 186
            |..::..|:|......|.::.|...|     :.:..|.|.|.:..|.:.||.::....|.||:|
Frog   114 SPEITTDDIKAAFAPFGRISDARVVKDMTTGKSKGYGFVSFFNKWDAENAIAQMGGQWLGGRQI 177

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
B52	NP_001014619.2	RRM1_SRSF4_like	5..74	CDD:240783	22/73 (30%)
B52	NP_001014619.2	RRM2_SRSF4_like	120..191	CDD:241044	18/72 (25%)
tia1	XP_012814227.2	RRM1_TIA1	8..81	CDD:410027	21/71 (30%)
		RRM2_TIA1	104..181	CDD:410030	18/74 (24%)
		RRM3_TIAR	214..286	CDD:241064
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910