DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment B52 and cstf2

DIOPT Version :9

Sequence 1:	NP_001014619.2	Gene:	B52 / 41670	FlyBaseID:	FBgn0004587	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	XP_009289373.1	Gene:	cstf2 / 386806	ZFINID:	ZDB-GENE-031118-2	Length:	508	Species:	Danio rerio

Alignment Length:	185	Identity:	44/185 - (23%)
Similarity:	64/185 - (34%)	Gaps:	72/185 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VYVGGLPYGVRERDLERFFKGYGRT--------RDILIKNGYGFVEFEDYRDADDAVYELNGKEL 62
            |:||.:||...|..|:..|...|..        |:.....||||.|::|...|..|:..|||:|.
Zfish    26 VFVGNIPYEATEEQLKDIFSEVGLVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRNLNGREF 90

  Fly    63 LGERVVVEPARGTARGSNRDRYDDRYGGRRGGGGGRYNEKNKNSRSS---------SRYG----- 113
            .|..:.|:.|.                          :||||....|         |.||
Zfish    91 SGRALRVDNAA--------------------------SEKNKEELKSLGTGAPIIESPYGDGCMP 129

  Fly   114 --------------PP-----LRTEYRLIVENLSSRVSWQDLKDYMRQAGEVTYA 149
                          ||     |..:.:|.|:|     |.|:.::.:.|..::.||
Zfish   130 EEAPESISRAVASLPPEQMFELMKQMKLCVQN-----SPQEARNMLLQNPQLAYA 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
B52	NP_001014619.2	RRM1_SRSF4_like	5..74	CDD:240783	25/75 (33%)
B52	NP_001014619.2	RRM2_SRSF4_like	120..191	CDD:241044	8/30 (27%)
cstf2	XP_009289373.1	RRM	<24..>112	CDD:223796	29/111 (26%)
		RRM_CSTF2_CSTF2T	26..100	CDD:241115	24/73 (33%)
		CSTF2_hinge	121..199	CDD:291025	14/64 (22%)
		CSTF_C	464..504	CDD:291002
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900