DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment B52 and tia1l

DIOPT Version :9

Sequence 1:	NP_001014619.2	Gene:	B52 / 41670	FlyBaseID:	FBgn0004587	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	NP_956476.1	Gene:	tia1l / 323447	ZFINID:	ZDB-GENE-030131-2167	Length:	342	Species:	Danio rerio

Alignment Length:	192	Identity:	44/192 - (22%)
Similarity:	77/192 - (40%)	Gaps:	45/192 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VYVGGLPYGVRERDLERFFKGYGRTRD---ILIKNG---YGFVEFEDYRDADDAVYELNGKELLG 64
            :|||.|...|.|..:.:.|...|..:.   ||...|   |.||||.:.|.|..|:..:||:::||
Zfish    11 LYVGNLSRDVTEALILQVFSQIGPCKSCKMILDTTGNDPYCFVEFYENRHAAAALAAMNGRKILG 75

  Fly    65 ERVVVEPARGTARGSNRDRYDDRYGGRRGGGGGRYNEKNKNSRSSSRYGPPLRTEYRLIVENLSS 129
            :.:.|..| .|.....:|                                 ....:.:.|.:||.
Zfish    76 KDMKVNWA-STPSSQKKD---------------------------------TSNHFHVFVGDLSP 106

  Fly   130 RVSWQDLKDYMRQAGEVTYADAHK-----QRRNEGVVEFASLSDMKTAIEKLDDTELNGRRI 186
            .:|..|::......|:::.|...|     :.:..|.:.|.:..|.::||::::...|.||:|
Zfish   107 EISTDDVRAAFAPFGKISDARVVKDLATGKSKGYGFISFINKWDAESAIQQMNGQWLGGRQI 168

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
B52	NP_001014619.2	RRM1_SRSF4_like	5..74	CDD:240783	25/73 (34%)
B52	NP_001014619.2	RRM2_SRSF4_like	120..191	CDD:241044	17/72 (24%)
tia1l	NP_956476.1	ELAV_HUD_SF	7..272	CDD:273741	44/192 (23%)
		RRM_SF	10..90	CDD:302621	26/79 (33%)
		RRM2_TIA1	96..175	CDD:241062	17/73 (23%)
		RRM3_TIAR	206..278	CDD:241064
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810