Protein Alignment B52 and Ncl

DIOPT Version :10

• Sequence 1: NP_788671.2
• Gene: B52 / 41670
• FlyBaseID: FBgn0004587
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: NP_036881.2
• Gene: Ncl / 25135
• RGDID: 3153
• Length: 714
• Species: Rattus norvegicus
• Alignment Length: 258
• Identity: 66/258 - (25%)
• Similarity: 97/258 - (37%)
• Gaps: 73/258 - (28%)

  Fly     8 VGGLPYGVRERDLERFFK----------GYGRTRDILIKNGYGFVEFEDYRDADDAVYELNGKEL 62
            :..|.|...|..|:..|:          .:|:::      ||.|:||..:.||.:|:...|..|:
  Rat   494 LSNLSYSATEETLQEVFEKATFIKVPQNPHGKSK------GYAFIEFASFEDAKEALNSCNKMEI 552

  Fly    63 LGERVVVEPARGTARGSNRDRYDDRYGGRRGGGGGRYNEKNKNSRSSSRYGPPLRTEYRLIVENL 127
            .|..:.:|                 ..|.||         :.|:||.     |.:|   |.|:.|
  Rat   553 EGRTIRLE-----------------LQGPRG---------SPNARSQ-----PSKT---LFVKGL 583

  Fly   128 SSRVSWQDLKDYMR---QAGEVTYADAHKQRRNEGVVEFASLSDMKTAIEKLDDTELNGRRIHL- 188
            |...:.:.||:...   :|..||..:.... :..|.|:|.|..|.|.|.|.::|.|::|.::.|
  Rat   584 SEDTTEETLKESFEGSVRARIVTDRETGSS-KGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLD 647

  Fly   189 -----VEDRRGGRSGGGGG-SGRGRSRSSSSRSRSRSRRRSRSRRSSHSRSKSRSRSKSRGGR 245
                 .|...|||.||.|| .|||..|.            .|.......|.....|...||||
  Rat   648 WAKPKGEGGFGGRGGGRGGFGGRGGGRG------------GRGGFGGRGRGGFGGRGGFRGGR 698

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B52	NP_788671.2	RRM1_SRSF4_like	5..74	CDD:409774	18/75 (24%)
		RRM2_SRSF4_like	120..191	CDD:410012	21/79 (27%)
Ncl	NP_036881.2	8 X 8 AA tandem repeats of X-T-P-X-K-K-X-X	58..135
		RRM1_NCL	312..386	CDD:409837
		RRM2_NCL	395..470	CDD:409838
		RRM3_NCL	489..561	CDD:409839	18/89 (20%)
		RRM4_NCL	576..653	CDD:409840	22/80 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	646..714		20/65 (31%)