DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment B52 and Tial1

DIOPT Version :9

Sequence 1:	NP_001014619.2	Gene:	B52 / 41670	FlyBaseID:	FBgn0004587	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	NP_033409.1	Gene:	Tial1 / 21843	MGIID:	107913	Length:	392	Species:	Mus musculus

Alignment Length:	209	Identity:	45/209 - (21%)
Similarity:	79/209 - (37%)	Gaps:	62/209 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VYVGGLPYGVRERDLERFFKGYGRTRDILI-----------------------KNGYGFVEFEDY 47
            :|||.|...|.|..:.:.|...|..:...:                       .:.|.||||.::
Mouse    11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSNDPYCFVEFYEH 75

  Fly    48 RDADDAVYELNGKELLGERVVVEPARGTARGSNRDRYDDRYGGRRGGGGGRYNEKNKNSRSSSRY 112
            |||..|:..:||:::||:.|.|..|  |...|.:                         :.:|.:
Mouse    76 RDAAAALAAMNGRKILGKEVKVNWA--TTPSSQK-------------------------KDTSNH 113

  Fly   113 GPPLRTEYRLIVENLSSRVSWQDLKDYMRQAGEVTYADAHK-----QRRNEGVVEFASLSDMKTA 172
                   :.:.|.:||..::.:|:|......|:::.|...|     :.:..|.|.|.:..|.:.|
Mouse   114 -------FHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENA 171

  Fly   173 IEKLDDTELNGRRI 186
            |..:....|.||:|
Mouse   172 IVHMGGQWLGGRQI 185

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
B52	NP_001014619.2	RRM1_SRSF4_like	5..74	CDD:240783	24/90 (27%)
B52	NP_001014619.2	RRM2_SRSF4_like	120..191	CDD:241044	18/72 (25%)
Tial1	NP_033409.1	RRM1_TIAR	10..107	CDD:410028	26/97 (27%)
		RRM2_TIAR	113..192	CDD:410029	18/80 (23%)
		RRM3_TIAR	222..294	CDD:241064
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	363..392
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900