DRSC/TRiP Functional Genomics Resources

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Protein Alignment B52 and Tia1

DIOPT Version :10

Sequence 1:NP_788671.2 Gene:B52 / 41670 FlyBaseID:FBgn0004587 Length:355 Species:Drosophila melanogaster
Sequence 2:NP_035715.1 Gene:Tia1 / 21841 MGIID:107914 Length:386 Species:Mus musculus


Alignment Length:194 Identity:48/194 - (24%)
Similarity:81/194 - (41%) Gaps:38/194 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 VYVGGLPYGVRERDLERFFKGYGRTR------DILIKNGYGFVEFEDYRDADDAVYELNGKELLG 64
            :|||.|...|.|..:.:.|...|..:      |....:.|.||||.::|.|..|:..:||::::|
Mouse     9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNGRKIMG 73

  Fly    65 ERVVVEPARGTARGSNRDRYDDRYGGRRGGGGGRYNEKNKNSRSSSRYGPPLRTE--YRLIVENL 127
            :.|.|..|  |...|                       .|...|||......|::  :.:.|.:|
Mouse    74 KEVKVNWA--TTPSS-----------------------QKKDTSSSTVVSTQRSQDHFHVFVGDL 113

  Fly   128 SSRVSWQDLKDYMRQAGEVTYADAHK-----QRRNEGVVEFASLSDMKTAIEKLDDTELNGRRI 186
            |..::.:|:|......|.::.|...|     :.:..|.|.|.:..|.:.||:::....|.||:|
Mouse   114 SPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQI 177

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
B52NP_788671.2 RRM1_SRSF4_like 5..74 CDD:409774 23/73 (32%)
RRM2_SRSF4_like 120..191 CDD:410012 18/72 (25%)
Tia1NP_035715.1 RRM1_TIA1 8..81 CDD:410027 22/71 (31%)
RRM2_TIA1 104..181 CDD:410030 18/74 (24%)
RRM3_TIAR 214..286 CDD:241064
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 355..376
Blue background indicates that the domain is not in the aligned region.

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